China Factory Direct
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| CAS number | 3304-51-6 |
| Product name | N'-Cbz-L-ornithine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
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| Pharmaceutical R&D | Chiral intermediates for synthesizing antiviral agents (e.g., HIV protease inhibitors) and peptide-based therapeutics | Deprotection (e.g., catalytic hydrogenolysis with H₂/Pd-C) or coupling reactions (e.g., DIC/HOBt-mediated condensation) in inert solvents (e.g., THF, DCM) to introduce the target molecule |
| Peptide Synthesis | Temporary protection of the ornithine side-chain amino group to prevent side reactions | Used as an Nα-protecting group in solid-phase peptide synthesis (SPPS); the Cbz group stabilizes the α-amino group and is subsequently removed selectively |
| Biochemical Research | Preparation of isotopically or fluorescently labeled ornithine derivatives for metabolic pathway tracing | Selective functionalization (e.g., alkylation, acylation) following Cbz protection, followed by deprotection to yield functionalized ornithine probes |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a certified reference standard using reversed-phase chromatography and UV detection at 210 nm. |
| Related Substances | HPLC-UV | Separation and detection of structurally related impurities (e.g., N-Cbz-ornithine diastereomers, deprotected ornithine, hydrolysis products) using gradient HPLC-UV. |
| Chiral Purity | Chiral HPLC | Enantioselective separation on a chiral stationary phase to determine L-enantiomer excess relative to D-ornithine or racemate. |
| Residual Solvents | GC-FID | Quantitative determination of Class 2/3 residual solvents (e.g., methanol, ethyl acetate, toluene) using gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content based on stoichiometric reaction. |
| Heavy Metals | ICP-OES | Multi-element quantification of toxic metals (Pb, Cd, As, Hg, Ni) after acid digestion, using inductively coupled plasma optical emission spectrometry. |
| Residue on Ignition | Gravimetric Analysis | Measurement of inorganic ash content after high-temperature incineration at 700-800 C followed by weighing of residue. |
| Specific Optical Rotation | Polarimetry | Determination of chiral compound concentration and enantiomeric integrity by measuring rotation of plane-polarized light at 589 nm. |
| pH (1% w/v aqueous solution) | Potentiometric pH Measurement | Direct measurement using calibrated glass electrode in a standardized aqueous suspension/solution. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample to determine D10, D50, D90 values based on light scattering patterns. |
| Microbial Contamination | Membrane Filtration | Quantitative detection of aerobic microorganisms and absence of specified pathogens (e.g., E. coli, S. aureus) per pharmacopeial methods. |
| Loss on Drying | Thermogravimetric Analysis | Weight loss measurement after drying at 105 C under vacuum or nitrogen to determine volatile content including residual moisture and solvents. |
| Test Item | Specification |
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| Appearance | White powder |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 132~136°C |
| Optical Rotation | +19.0 to +23.0° (c=1, in 1M HCl) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.