4,6-DICHLORO-2-(METHYLTHIO)PYRIMIDINE-5-CARBONITRILE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 33097-13-1 |
| Product name | 4,6-DICHLORO-2-(METHYLTHIO)PYRIMIDINE-5-CARBONITRILE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4,6-DICHLORO-2-(METHYLTHIO)PYRIMIDINE-5-CARBONITRILE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4,6-DICHLORO-2-(METHYLTHIO)PYRIMIDINE-5-CARBONITRILE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4,6-DICHLORO-2-(METHYLTHIO)PYRIMIDINE-5-CARBONITRILE
| Industry | Application | Process |
|---|---|---|
| Pesticides | Synthesis of fungicidal intermediates | Multi-step synthesis involving chlorination, cyanation, and methylthiolation, applied in the preparation of pyrimidine-based active ingredients |
| Chemical Intermediates | Organic synthesis; precursor for pharmaceuticals and agrochemicals | Nucleophilic substitution and cyclization reactions conducted in specific solvents to construct the pyrimidine ring structure |
| Pharmaceuticals | Synthetic intermediate for antitumor or antibacterial agents | Functional group introduction via coupling reactions, applied in the construction of biologically active pyrimidine derivatives |
Manufacturing Quality Control of 4,6-DICHLORO-2-(METHYLTHIO)PYRIMIDINE-5-CARBONITRILE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and relative response factors. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, acetone, DMF) based on calibrated external standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine generation in pyridine-free reagent; measures water via stoichiometric reaction with iodine and sulfur dioxide. |
| Heavy Metals | ICP-OES | Multi-element quantification after acid digestion using inductively coupled plasma optical emission spectrometry with matrix-matched calibration. |
| Chloride Impurity | Ion Chromatography | Separation of chloride anion on an anion-exchange column with suppressed conductivity detection; quantified using external calibration. |
| Sulfur Content (as Methanethiol-derived) | Combustion IC | High-temperature combustion followed by ion chromatographic detection of sulfate; measures total organic sulfur converted to sulfate. |
| Particle Size Distribution | Laser Diffraction | Dry or wet dispersion followed by light scattering analysis to determine volume-based particle size distribution (D10, D50, D90). |
| Bulk Density | USP <616> Tap Density Method | Measurement of mass per unit volume after controlled tapping; determines both bulk and tapped density for flowability assessment. |
| Melting Point | Capillary Melting Point Apparatus | Thermal analysis using capillary tube method per USP <741>; detects temperature range of solid-to-liquid phase transition. |
| Residue on Ignition | Gravimetric Analysis | Ignition at 700-800 C followed by weighing of non-volatile inorganic residue; measures inorganic ash content. |
| Microbial Contamination | Membrane Filtration | Filtration of sample solution through sterile membrane, followed by incubation on soybean-casein digest agar and trypticase soy agar for aerobic microbial count. |
Technical Specifications of 4,6-DICHLORO-2-(METHYLTHIO)PYRIMIDINE-5-CARBONITRILE
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4,6-DICHLORO-2-(METHYLTHIO)PYRIMIDINE-5-CARBONITRILE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4,6-DICHLORO-2-(METHYLTHIO)PYRIMIDINE-5-CARBONITRILE
Safety Information of 4,6-DICHLORO-2-(METHYLTHIO)PYRIMIDINE-5-CARBONITRILE
| Pictograms |   |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 4,6-DICHLORO-2-(METHYLTHIO)PYRIMIDINE-5-CARBONITRILE
Industrial 4,6-DICHLORO-2-(METHYLTHIO)PYRIMIDINE-5-CARBONITRILE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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