N-Cbz-N-methyl-L-leucine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 33099-08-0 |
| Product name | N-Cbz-N-methyl-L-leucine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for N-Cbz-N-methyl-L-leucine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk N-Cbz-N-methyl-L-leucine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of N-Cbz-N-methyl-L-leucine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Synthesis | Used as an amino-protecting group in solid-phase or solution-phase synthesis of peptides and drug molecules | In peptide synthesis, the amino group of leucine is protected with N-carbobenzoxy (Z) to prevent side reactions; deprotection is subsequently achieved via hydrogenolysis or acidolysis |
| Chemical Intermediates | Used in the synthesis of biologically active peptides and protease inhibitors | Employed as a chiral building block in condensation reactions to form peptide bonds, commonly coupled with other protected amino acids |
| Biochemical Research | Used as a reference standard or intermediate for studying amino acid metabolism and enzyme mechanisms | Serves as a substrate or inhibitor precursor in in vitro enzymatic reactions for kinetic analysis |
Manufacturing Quality Control of N-Cbz-N-methyl-L-leucine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a reference standard using reversed-phase chromatography and UV detection at 210 nm. |
| Related Substances | HPLC-UV | Separation and quantification of structurally related impurities using gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Detection and quantification of volatile organic solvents based on retention time and flame ionization response. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine generated in situ to determine water content via stoichiometric reaction. |
| Optical Rotation | [alpha]D Measurement | Measurement of specific rotation using a polarimeter to confirm chiral integrity and enantiomeric purity. |
| Heavy Metals | ICP-OES | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion and plasma excitation. |
| Chloride Content | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column and conductivity detection. |
| Residue on Ignition | Gravimetric Analysis | Determination of inorganic ash content by high-temperature incineration followed by weight measurement. |
| pH (1% w/v aqueous solution) | pH Potentiometry | Measurement of hydrogen ion activity using calibrated glass electrode in aqueous suspension. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition determination by observing solid-to-liquid phase change under controlled heating. |
| Particle Size Distribution | Laser Diffraction | Analysis of particle size based on angular scattering pattern of laser light passing through dispersed sample. |
| Microbial Limits | Membrane Filtration and Plate Count | Enumeration of aerobic microorganisms after filtration, membrane transfer, and incubation on nutrient agar. |
Technical Specifications of N-Cbz-N-methyl-L-leucine
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 72-76°C |
| Optical Rotation | -15.0° to -19.0° (c=1, in CHCl3) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of N-Cbz-N-methyl-L-leucine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of N-Cbz-N-methyl-L-leucine
Packaging of N-Cbz-N-methyl-L-leucine
Industrial N-Cbz-N-methyl-L-leucine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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