China Factory Direct
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| CAS number | 33142-21-1 |
| Product name | 2-Chloro-3-oxopropionic acid ethyl ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of β-lactam antibiotics (e.g., cephalosporins) | Condenses with imines or amines to construct the β-lactam ring |
| Agrochemicals | Preparation of novel insecticides and fungicides containing the β-lactam moiety | Acts as an active acylating agent in cyclization reactions to introduce the chloroformylacetyl group |
| Organic Synthesis | Multifunctional acylating agent for introducing the chloroformylacetyl group (–CH₂C(O)COCl) | Reacts with nucleophiles such as alcohols, amines, and phenols under anhydrous, low-temperature conditions to yield corresponding esters, amides, or carbonates |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detection | Quantitative determination based on peak area comparison against a certified reference standard using a calibrated GC system. |
| Water Content | Karl Fischer Titration | Electrochemical titration where iodine reacts stoichiometrically with water in a methanol-based reagent; endpoint detected amperometrically. |
| Acid Value | Acid-Base Titration with NaOH | Neutralization of acidic impurities (e.g., residual chloroacetic acid) using standardized sodium hydroxide solution and phenolphthalein indicator. |
| Residue on Ignition | Gravimetric Analysis | Measurement of non-volatile inorganic residue after controlled high-temperature ashing and subsequent weighing. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and quantification of chloride ions using anion-exchange column and conductivity detection. |
| Heavy Metals | ICP-OES | Multi-element detection of metallic contaminants (e.g., Pb, Cd, Hg, As) after acid digestion, based on element-specific atomic emission intensities. |
| Color | Visual Comparison to APHA Scale | Subjective assessment of liquid color intensity by comparing sample against platinum-cobalt standard solutions under controlled lighting. |
| Density | Digital Density Meter | Determination of mass per unit volume at specified temperature using oscillating U-tube principle. |
| Refractive Index | Refractometry | Measurement of light bending angle at air-sample interface using calibrated refractometer at 20 degrees C. |
| Volatility Residue | Gas Chromatography-Mass Spectrometry (GC-MS) | Identification and semi-quantitative assessment of volatile organic impurities co-eluting or near the main peak. |
| Aldehyde Impurity | UV-Vis Spectrophotometry | Quantification of aldehyde-related chromophores (e.g., after derivatization with DNPH) via absorbance at characteristic wavelength. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through a solution, indicating chiral impurity content if applicable. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.5% (by GC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.3% |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
| Odor | Characteristic ester-like odor |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.