China Factory Direct
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| CAS number | 33208-99-0 |
| Product name | L-Alaninamide hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Reagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Building block for synthesis of antiviral agents (e.g., adefovir ester derivatives) and peptide-based therapeutics | Used as a chiral building block in solid-phase or solution-phase peptide synthesis; L-alanine residue introduced via amide bond coupling |
| Organic Synthesis | Chiral auxiliary or amino-protecting form in asymmetric synthesis | HCl salt protecting group removed under basic conditions to liberate free L-alaninamide for condensation, cyclization, and related reactions |
| Analytical Chemistry | Reference standard or derivatization reagent in high-performance liquid chromatography (HPLC) and mass spectrometry (MS) | Condenses with aldehydes or ketones to form Schiff bases, enhancing detection sensitivity and selectivity |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Acid-Base Titration | Quantifies L-alaninamide hydrochloride by titration with standardized NaOH using an acid-base indicator or potentiometric endpoint detection. |
| Loss on Drying | Gravimetric Analysis | Measures weight loss after drying at specified temperature and time to determine volatile content including moisture and residual solvents. |
| Residual Solvents | Gas Chromatography (GC) | Separates and quantifies organic solvents (e.g., methanol, acetone) using a capillary column and flame ionization detection. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) | Determines total heavy metal content (as Pb) by atomizing the sample in a graphite furnace or flame and measuring absorbance at characteristic wavelengths. |
| Chloride Content | Potentiometric Titration | Measures chloride ions via titration with silver nitrate using a silver/silver chloride electrode for endpoint detection. |
| Specific Optical Rotation | Polarimetry | Measures the angle of rotation of plane-polarized light caused by chiral L-alaninamide hydrochloride in solution. |
| pH of Aqueous Solution | pH Meter Measurement | Determines hydrogen ion activity in a defined aqueous solution using a calibrated glass electrode system. |
| Related Substances | High-Performance Liquid Chromatography (HPLC) | Separates and quantifies structurally related impurities using reversed-phase C18 column and UV detection. |
| Water Content | Karl Fischer Titration | Quantifies water via stoichiometric reaction between iodine, sulfur dioxide, and water in a methanol-based reagent. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing of the sample. |
| Microbial Limits | Membrane Filtration | Detects and enumerates aerobic microorganisms by filtering sample through membrane, culturing on appropriate media, and counting colonies. |
| Particle Size Distribution | Laser Diffraction | Determines size distribution of solid particles by analyzing angular variation in laser light scattering pattern. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 178–182°C |
| Optical Rotation | +9.0 to +13.0° (c=1, in 1M HCl) |
| Total Impurities | <=1.5% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.