China Factory Direct
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| CAS number | 3332-29-4 |
| Product name | Ethoxyamine hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key side-chain reagent for synthesizing β-lactam antibiotics (e.g., cephalosporins) | Condensed with 7-ACA or 7-ADCA under low-temperature, alkaline conditions to form amide bonds |
| Pesticide Intermediates | Used to prepare oxime ether-containing insecticides and fungicides (e.g., strobilurin derivatives) | Reacted with aldehydes/ketones to form oxime ethers, followed by alkylation modification |
| Organic Synthesis | Reagent for introducing amino-protecting groups in peptide and complex molecule synthesis | Reacted with carboxylic acid derivatives (e.g., acid chlorides) under mild alkaline conditions to form cleavable ethoxyimino protecting groups |
| Test Item | Common Testing Method | Method Overview |
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| Assay | High-Performance Liquid Chromatography (HPLC) | Reverse-phase HPLC is used with a C18 column as the stationary phase and a mixture of phosphate buffer and organic solvent (e.g., methanol) as the mobile phase. The main component is detected by a UV detector (typically at 254 nm), and its concentration is calculated using external or internal standard methods. This method offers high sensitivity and accuracy. |
| Purity Analysis | Gas Chromatography (GC) | Suitable for analyzing volatile impurities or residual solvents. Ethoxyamine hydrochloride is derivatized into a volatile derivative, separated on a capillary column, and detected by a flame ionization detector (FID), allowing assessment of the main component's purity and impurity levels. |
| Impurity Testing | HPLC-UV or HPLC-MS | High-performance liquid chromatography coupled with UV or mass spectrometry detection enables simultaneous identification and quantification of various potential impurities (e.g., synthesis intermediates, degradation products). It is particularly effective for separating and identifying structurally similar impurities. |
| Residual Solvents | Gas Chromatography (GC-FID/MS) | Detects organic solvents introduced during manufacturing (e.g., ethanol, acetone, dichloromethane). Headspace sampling is employed, followed by separation on a capillary column and quantification using flame ionization detection (FID) or mass spectrometry (MS), in compliance with ICH Q3A guidelines. |
| pH Measurement | pH Meter Method | A solution of ethoxyamine hydrochloride at a defined concentration is prepared, and the pH of the aqueous solution is directly measured using a calibrated pH meter. Ensures the product remains within the specified range (typically pH 4.0–6.5), reflecting its acid-base stability. |
| Loss on Drying | Oven Drying Method (Constant Temperature) | The sample is placed in a drying oven at 105°C until constant weight is achieved. The percentage weight loss is calculated to assess moisture content and ensure product quality and stability. |
| Heavy Metal Testing | Atomic Absorption Spectroscopy (AAS) | Uses an atomic absorption spectrophotometer to determine trace levels of heavy metals such as lead, cadmium, and mercury. This highly sensitive method complies with pharmacopoeial requirements (e.g., Chinese Pharmacopoeia, USP) for heavy metal limits. |
| Ultraviolet-Visible Spectroscopy (UV-Vis) | UV-Vis Spectrophotometry | The UV-Vis absorption spectrum of an ethoxyamine hydrochloride solution is scanned between 200–400 nm to identify characteristic absorption peaks and their absorbance values. Used for preliminary identification and as support for assay determination. |
| Infrared Spectroscopy (IR) | Fourier Transform Infrared Spectroscopy (FTIR) | The infrared absorption spectrum of the sample is obtained and compared with that of a reference standard to confirm molecular structural features. Used for qualitative identification of active pharmaceutical ingredients or formulations. |
| Test Item | Specification |
|---|---|
| Appearance | White to almost white powder or crystals |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Melting Point | 128-132°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
| Odor | Characteristic, mild amine-like |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.