(S)-3-Aminopiperidine dihydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 334618-07-4 |
| Product name | (S)-3-Aminopiperidine dihydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (S)-3-Aminopiperidine dihydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (S)-3-Aminopiperidine dihydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (S)-3-Aminopiperidine dihydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral synthetic intermediate for antiviral, anticancer, and central nervous system (CNS) drugs (e.g., HIV integrase inhibitors, NK1 receptor antagonists) | Used as a chiral building block in multistep asymmetric synthesis, including coupling, acylation, and reductive amination; typically reacted with borane complexes or phosgene derivatives under low-temperature, inert-atmosphere conditions to construct the target molecular scaffold |
| Fine Chemicals | Precursor for chiral catalyst ligands | After N-protection, coordinated with transition metals (e.g., Pd, Ir) to enable asymmetric allylation, hydrogenation, and other catalytic reactions |
Manufacturing Quality Control of (S)-3-Aminopiperidine dihydrochloride
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 210 nm, comparing peak area to a reference standard. |
| Enantiomeric Purity | Chiral HPLC | Resolves (S)- and (R)-enantiomers on a chiral stationary phase; enantiomeric excess calculated from peak area ratio. |
| Water Content | Karl Fischer Titration | Measures water by coulometric or volumetric titration using iodine-based reagent in methanol/pyridine solvent system. |
| Residual Solvents | GC-FID | Detects and quantifies volatile organic solvents (e.g., ethanol, acetone) using capillary GC with flame ionization detection. |
| Heavy Metals | ICP-MS | Quantifies trace metals (Pb, Cd, Hg, As) after acid digestion by measuring elemental mass-to-charge ratios with high sensitivity. |
| Chloride Content | Potentiometric Titration | Determines chloride ions using silver nitrate titrant with silver indicator electrode and reference electrode. |
| pH of Aqueous Solution | pH Meter Measurement | Measures hydrogen ion activity in 1% w/v aqueous solution using calibrated glass electrode pH meter. |
| Related Substances | HPLC-UV | Identifies and quantifies impurities (e.g., starting materials, degradants) via gradient HPLC with UV detection. |
| Loss on Drying | Gravimetric Analysis | Determines volatile content by measuring weight loss after drying at 105 C for 2 hours under vacuum. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles against established visual standards under controlled lighting. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary apparatus per USP <741>. |
| Microbial Limits | Membrane Filtration | Quantifies aerobic microorganisms and detects specified pathogens (e.g., E. coli) following USP <61> and <62>. |
Technical Specifications of (S)-3-Aminopiperidine dihydrochloride
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | +1.5° to +2.5° (c=1, in H2O) |
| Melting Point | 245°C to 255°C (decomposes) |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (S)-3-Aminopiperidine dihydrochloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (S)-3-Aminopiperidine dihydrochloride
Safety Information of (S)-3-Aminopiperidine dihydrochloride
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of (S)-3-Aminopiperidine dihydrochloride
Industrial (S)-3-Aminopiperidine dihydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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