(2S,5S)-N-Boc-5-methylpyrrolidine-2-carboxylic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 334769-80-1 |
| Product name | (2S,5S)-N-Boc-5-methylpyrrolidine-2-carboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (2S,5S)-N-Boc-5-methylpyrrolidine-2-carboxylic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (2S,5S)-N-Boc-5-methylpyrrolidine-2-carboxylic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (2S,5S)-N-Boc-5-methylpyrrolidine-2-carboxylic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral intermediates for synthesizing antiviral agents (e.g., HCV NS5A inhibitors) and neuroactive compounds | Used in asymmetric synthesis, chiral resolution, and coupling reactions (e.g., Suzuki coupling, amide coupling) |
| Pharmaceutical R&D | Building blocks for candidate drug molecules containing a 5-methylpyrrolidine scaffold, employed in structure–activity relationship (SAR) studies | Applied as a key chiral building block in multistep organic synthesis, including cyclization, N-Boc deprotection, and functional group transformations |
| Fine Chemicals | High-purity chiral excipients or precursors to catalyst ligands | Processed via crystallization purification, chromatographic separation, and selective Boc group introduction/removal |
Manufacturing Quality Control of (2S,5S)-N-Boc-5-methylpyrrolidine-2-carboxylic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 210 nm, comparing peak area to a certified reference standard. |
| Chiral Purity | Chiral HPLC | Separation of enantiomers on a chiral stationary phase, with UV detection to determine enantiomeric excess (ee). |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Coulometric or volumetric titration using iodine-based reagent to determine trace water content. |
| Heavy Metals | ICP-MS | Multi-element detection and quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion. |
| Residual Palladium | ICP-OES | Quantification of palladium catalyst residue using inductively coupled plasma optical emission spectroscopy. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities using gradient reverse-phase HPLC with UV detection. |
| Residual Boc Reagent | GC-MS | Identification and quantification of di-tert-butyl dicarbonate and tert-butanol by gas chromatography-mass spectrometry. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to confirm chiral integrity and identity. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid transition temperature range as a physical identity and purity indicator. |
| Particle Size Distribution | Laser Diffraction | Measurement of particle size distribution in dry powder form using laser scattering principles. |
| Residual Chloride | Ion Chromatography | Quantification of chloride ion impurity using suppressed conductivity detection after anion exchange separation. |
Technical Specifications of (2S,5S)-N-Boc-5-methylpyrrolidine-2-carboxylic acid
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78-82°C |
| Optical Rotation | -94° to -90° (c=1, in CHCl3) |
| Identification (NMR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (2S,5S)-N-Boc-5-methylpyrrolidine-2-carboxylic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (2S,5S)-N-Boc-5-methylpyrrolidine-2-carboxylic acid
Safety Information of (2S,5S)-N-Boc-5-methylpyrrolidine-2-carboxylic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of (2S,5S)-N-Boc-5-methylpyrrolidine-2-carboxylic acid
Industrial (2S,5S)-N-Boc-5-methylpyrrolidine-2-carboxylic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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