2-CHLORO-7H-PYRROLO[2,3-D]PYRIMIDINE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 335654-06-3 |
| Product name | 2-CHLORO-7H-PYRROLO[2,3-D]PYRIMIDINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-CHLORO-7H-PYRROLO[2,3-D]PYRIMIDINE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-CHLORO-7H-PYRROLO[2,3-D]PYRIMIDINE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-CHLORO-7H-PYRROLO[2,3-D]PYRIMIDINE
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Key intermediate for synthesizing kinase inhibitors in the development of anticancer, anti-inflammatory, and autoimmune disease therapeutics | Used to construct active molecular scaffolds via nucleophilic substitution, Suzuki coupling, or Buchwald–Hartwig amination |
| Agrochemical R&D | Employed in synthesizing bioactive heterocyclic compounds for discovery of novel herbicides or fungicides | Serves as a nitrogen-containing heterocyclic core structure in multistep organic synthesis |
| Chemical Research | Building block for constructing complex heterocyclic systems in medicinal chemistry and chemical biology research | Used as a starting material in palladium-catalyzed cross-coupling, cyclization, and functional group transformations |
Manufacturing Quality Control of 2-CHLORO-7H-PYRROLO[2,3-D]PYRIMIDINE
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Identification | Infrared Spectroscopy (IR) Proton Nuclear Magnetic Resonance (¹H NMR) Mass Spectrometry (MS) |
Confirm the compound's structure as 2-chloro-7H-pyrrolo[2,3-d]pyrimidine based on characteristic IR absorption peaks, ¹H NMR chemical shifts and coupling constants, and molecular ion and fragment ions observed in mass spectrometry. |
| Assay | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with an appropriate water-organic solvent (e.g., methanol or acetonitrile) mobile phase, UV detection (typically around 254 nm), and calculate the main component content using external standard or area normalization method. |
| Related Substances / Impurity Testing | High-Performance Liquid Chromatography (HPLC) | Employ gradient or isocratic elution to separate the main peak from potential process-related impurities (e.g., unreacted starting materials, by-products, degradation products). Assess each impurity’s level against specified limits using reference standards or self-reference methods. |
| Residual Solvents | Gas Chromatography (GC) | Follow ICH Q3C guidelines. Use headspace or direct injection with polar or non-polar capillary columns and FID detection to qualitatively and quantitatively analyze residual organic solvents (e.g., dichloromethane, methanol, DMF) from synthesis processes. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Oven Drying Method | Dry the sample at a specified temperature (e.g., 105°C) until constant weight is achieved, measuring the percentage loss in mass due to moisture or volatile components. |
| Residue on Ignition | High-Temperature Ashing Method | Ignite the sample at high temperature (typically 700–800°C) and determine the mass of inorganic residue (ash) to control inorganic impurities. |
| Water Content | Karl Fischer Titration | Quantitatively determine trace moisture content using the reaction between Karl Fischer reagent and water via titration (capacity or coulometric method). |
| Melting Point | Capillary Melting Point Determination | Determine the temperature range from initial melting to complete melting using a melting point apparatus, serving as a physical constant for auxiliary identification and purity assessment. |
Technical Specifications of 2-CHLORO-7H-PYRROLO[2,3-D]PYRIMIDINE
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 245–249 °C |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-CHLORO-7H-PYRROLO[2,3-D]PYRIMIDINE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-CHLORO-7H-PYRROLO[2,3-D]PYRIMIDINE
Safety Information of 2-CHLORO-7H-PYRROLO[2,3-D]PYRIMIDINE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2-CHLORO-7H-PYRROLO[2,3-D]PYRIMIDINE
Industrial 2-CHLORO-7H-PYRROLO[2,3-D]PYRIMIDINE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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