China Factory Direct
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| CAS number | 336100-47-1 |
| Product name | (S)-2-AMINO-3-METHOXY-PROPIONIC ACID HYDROCHLORIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral drug intermediates for synthesizing antiviral agents (e.g., HIV protease inhibitors) and neuroactive compounds | Purified via hydrochloride salt formation following chiral resolution or asymmetric synthesis |
| Pharmaceuticals | Synthetic precursor to L-methoxamine propionic acid derivatives, used in developing novel NMDA receptor modulators | Condensed with aldehydes or ketones to form imines, followed by reduction or cyclization to construct the target molecular scaffold |
| Biochemical Research | Chiral probe for studying substrate specificity of amino acid transporters (e.g., ASCT2) | Used as a competitive inhibitor or substrate in kinetic analyses within cellular or patch-clamp experiments |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC with Chiral Column | Enantioselective separation and UV detection to quantify the (S)-enantiomer content relative to a reference standard. |
| Related Substances | HPLC with UV Detection | Separation of impurities using reversed-phase chromatography and quantification by peak area comparison against reference standards. |
| Optical Rotation | [alpha]D Measurement | Measurement of specific rotation at 589 nm using a polarimeter to confirm chiral integrity and enantiomeric excess. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to identify and quantify organic solvent residues per ICH Q3C. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content in the sample. |
| Heavy Metals | ICP-MS | Quantitative determination of elemental impurities (e.g., Pb, Cd, Hg, As) after acid digestion and mass spectrometric detection. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using a silver indicator electrode to measure chloride ion concentration from hydrochloride salt. |
| pH of Aqueous Solution | pH Meter Measurement | Direct measurement of pH in a defined aqueous solution (e.g., 1% w/v) using calibrated pH electrode. |
| Loss on Drying | Gravimetric Thermogravimetry | Weight loss after drying under specified temperature and vacuum conditions to assess volatile and moisture content. |
| Residue on Ignition | Sulfated Ash Test | Ignition of sample with sulfuric acid followed by high-temperature ashing to quantify inorganic residue. |
| Microbial Contamination | Membrane Filtration | Enumeration of aerobic microorganisms and detection of specified pathogens per pharmacopeial methods (e.g., USP <61>). |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion using laser scattering to determine D10, D50, D90 values. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 178–182°C |
| Optical Rotation | +10.0 to +11.0° (c=1, in 1M HCl) |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.