China Factory Direct
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| CAS number | 33641-15-5 |
| Product name | 5-Hydroxy-1-methylpyrazole |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthetic intermediate for antiarrhythmic drugs (e.g., propafenone) | Chemical synthesis |
| Pharmaceuticals | Key raw material or intermediate for clopidogrel (antiplatelet agent) | Chemical synthesis |
| Pharmaceuticals | Intermediate for other fine chemical pharmaceuticals | Chemical synthesis |
| Agrochemicals | Intermediate for synthesis of pyrazole-based pesticides or plant growth regulators | Chemical synthesis |
| Test Item | Common Analytical Method | Method Description |
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| Content Determination | High-Performance Liquid Chromatography (HPLC) | A reverse-phase column (e.g., C18) is used with water-methanol or water-acetonitrile as the mobile phase. A UV detector (220–280 nm) is employed for detection, and external standard or internal standard methods are used for quantification of the main component. |
| Purity Analysis | High-Performance Liquid Chromatography (HPLC) | As above, peak area normalization is used to evaluate the purity of the main peak, detecting potential organic impurities and degradation products. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | An optimized gradient elution program is applied to separate and identify synthetic intermediates, by-products, or degradation impurities. Typically, a detection limit ≤ 0.05% is required. |
| Residual Solvents | Gas Chromatography (GC) | In accordance with ICH guidelines, a capillary column and FID detector are used to detect volatile organic solvents (e.g., methanol, ethanol, acetone) used during the manufacturing process. |
| Water Content | Karl Fischer Titration | Iodine and sulfur dioxide react with water in an anhydrous environment to precisely determine the water content in the sample, commonly used for API quality control. |
| Crystallinity Analysis | X-ray Powder Diffraction (XRD) | The crystal structure of solid samples is analyzed to confirm the presence of polymorphic forms, used for batch-to-batch consistency control. |
| Melting Point Determination | Capillary Melting Point Method or Automatic Melting Point Apparatus | The temperature range at which a compound transitions from solid to liquid is measured, serving as a physical property for identification and as an auxiliary indicator of purity. |
| Structure Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR), Mass Spectrometry (MS) | ¹H-NMR, ¹³C-NMR, and HRMS (High-Resolution Mass Spectrometry) are used to confirm molecular structures, typically for starting materials or new batch verification. |
| Solution Clarity and Color | Visual Color Comparison or UV-Visible Spectrophotometry | The sample is dissolved at a specific concentration, then compared with standard turbidity or color standards to assess the appearance quality of the solution. |
| pH Value (Solution) | pH Meter Measurement | The sample is dissolved in water or an appropriate solvent, and its acidity or alkalinity is measured using a calibrated pH meter to ensure suitability for formulation. |
| Test Item | Specification |
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| Appearance | Yellow solid |
| Purity | >=98.0% (GC) |
| Melting Point | 124–128°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.