China Factory Direct
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| CAS number | 33674-97-4 |
| Product name | (6-Chloro-2-pyridinyl)methanol |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of anticancer agents (e.g., gefitinib analogues) | Used to introduce the pyridine ring structure via nucleophilic substitution or coupling reactions, enabling construction of the active pharmaceutical ingredient scaffold |
| Agrochemicals | Intermediate in the synthesis of novel insecticides or herbicides | Applied in functional group transformations—such as chlorine or hydroxymethyl conversion—followed by coupling with other heterocyclic or aromatic structures to form target agrochemical molecules |
| Chemical Synthesis | Organic building block for nitrogen-containing heterocycle synthesis | Leverages dual reactivity of chlorine and hydroxymethyl groups for selective functionalization (e.g., etherification, amination, oxidation) |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-DAD or UPLC-MS | Separation and identification/quantification of structurally related impurities (e.g., 6-chloropyridine, 2-hydroxymethylpyridine, chlorinated dimers) using gradient elution and spectral or mass confirmation. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify residual solvents (e.g., methanol, dichloromethane, toluene) per ICH Q3C guidelines. |
| Chloride Ion Impurity | Ion Chromatography (IC) or Potentiometric Titration | Quantification of inorganic chloride via suppressed conductivity detection (IC) or argentometric titration with AgNO₃ endpoint detection. |
| Heavy Metals | ICP-MS or AAS | Determination of Pb, Cd, Hg, As, and other regulated metals after acid digestion, using inductively coupled plasma mass spectrometry or atomic absorption spectroscopy. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical quantification of water content based on the stoichiometric reaction of iodine with water in anhydrous methanol/pyridine medium. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement by observing solid-to-liquid phase change under controlled heating rate; used for identity and purity screening. |
| Appearance & Color | Visual Inspection / APHA Color Scale | Subjective assessment of physical state (crystalline powder) and color intensity compared to platinum-cobalt standards. |
| Residue on Ignition | Gravimetric Analysis | Measurement of non-volatile inorganic residue after high-temperature ashing (700–800 °C) and weighing. |
| Specific Optical Rotation | Polarimetry | Determination of chiral purity (if applicable) and identity verification using sodium D-line light through a solution in specified solvent and path length. |
| pH of Aqueous Solution | pH Meter | Measurement of hydrogen ion activity in a saturated aqueous suspension (1% w/v) using calibrated pH electrode. |
| Particle Size Distribution | Laser Diffraction | Analysis of particle size distribution based on angular variation in laser light scattering pattern of dispersed sample. |
| Microbial Limits | Membrane Filtration / Plate Count | Quantitative enumeration of aerobic microorganisms and absence testing for specified pathogens per pharmacopeial methods (e.g., USP <61>, <62>). |
| Test Item | Specification |
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| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 72-76°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.