Succinimido (S)-2-[(tert-butoxycarbonyl)amino]propionate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 3392-05-0 |
| Product name | Succinimido (S)-2-[(tert-butoxycarbonyl)amino]propionate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Succinimido (S)-2-[(tert-butoxycarbonyl)amino]propionate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Succinimido (S)-2-[(tert-butoxycarbonyl)amino]propionate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Succinimido (S)-2-[(tert-butoxycarbonyl)amino]propionate
| Industry | Application | Process |
|---|---|---|
| Biopharmaceuticals | Nα-protecting reagent for L-alanine residues in peptide synthesis | Used in solid-phase peptide synthesis (SPPS) as an active ester to mediate coupling reactions with amines, forming amide bonds and introducing the Boc protecting group; commonly applied for side-chain protection or construction of specialized sequences in Fmoc-based strategies |
| Organic Synthesis | Protected and activated intermediate for amino acid derivatives | Reacted selectively with primary or secondary amines under inert atmosphere in DMF or DCM to achieve N-acylation; the Boc group is subsequently removed using TFA |
| Pharmaceutical R&D | Structural modification reagent for small-molecule drugs and peptide-based candidate compounds | Employed as a key building block to construct alanine-containing pharmacophores, such as in synthetic routes for protease inhibitors and G protein-coupled receptor (GPCR) ligands |
Manufacturing Quality Control of Succinimido (S)-2-[(tert-butoxycarbonyl)amino]propionate
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 210 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., di-Boc derivatives, hydrolyzed acid) via gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., DCM, DMF, toluene) using gas chromatography with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration | Determines trace water by coulometric or volumetric titration based on the stoichiometric reaction of iodine with water in pyridine/methanol medium. |
| Optical Purity (Enantiomeric Excess) | Chiral HPLC | Separates enantiomers on a chiral stationary phase and calculates ee% from peak area ratio relative to L-enantiomer reference. |
| Heavy Metals | ICP-OES | Quantifies total heavy metals (Pb, Cd, Ni, Fe, Cu) after acid digestion by measuring atomic emission intensities at element-specific wavelengths. |
| Residual Palladium | ICP-MS | Detects trace Pd catalyst residues (pptr level) via inductively coupled plasma mass spectrometry using isotope 105Pd. |
| Acid Value | Acid-Base Titration | Measures free carboxylic acid groups by titration with standardized NaOH solution using phenolphthalein indicator. |
| Loss on Drying | Gravimetric Analysis | Determines volatile content by measuring weight loss after drying under controlled temperature and vacuum for fixed duration. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary method per USP <741>. |
| Particle Size Distribution | Laser Diffraction | Measures particle size distribution in dry powder mode using Mie scattering theory and calibrated optical model. |
| Microbial Contamination | Membrane Filtration | Detects aerobic microorganisms by filtration, membrane transfer to agar media, and colony enumeration after incubation per Ph. Eur. 2.6.12. |
Technical Specifications of Succinimido (S)-2-[(tert-butoxycarbonyl)amino]propionate
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 75–79°C |
| Optical Rotation | -55 to -49° (c=1, in DMF) |
| Identification (NMR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Succinimido (S)-2-[(tert-butoxycarbonyl)amino]propionate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Succinimido (S)-2-[(tert-butoxycarbonyl)amino]propionate
Safety Information of Succinimido (S)-2-[(tert-butoxycarbonyl)amino]propionate
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Succinimido (S)-2-[(tert-butoxycarbonyl)amino]propionate
Industrial Succinimido (S)-2-[(tert-butoxycarbonyl)amino]propionate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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