China Factory Direct
|
|
| CAS number | 3392-09-4 |
| Product name | BOC-LEU-OSU |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Synthesis | Used as a protecting group in peptide drug synthesis | Boc-Leu-Osu serves as the Boc (tert-butoxycarbonyl)-protected form of leucine and is commonly applied in solid-phase or solution-phase peptide synthesis to incorporate leucine into peptide chains via coupling reactions |
| Biochemical Research | Synthesis of amino acid derivatives and peptides | Reacted with amine compounds to form corresponding amides or peptide bonds for studying protein structure and function |
| Chemical Intermediate | Intermediate for synthesizing other organic compounds | Deprotected (e.g., via acidolysis) to yield free leucine, which subsequently participates in other organic synthesis reactions |
| Food Additives | Synthesis of specific amino acid derivatives | Applied in the food industry to prepare functional amino acid products, subject to compliance with relevant food safety regulations |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies Boc-Leu-Osu by reversed-phase HPLC with UV detection at 210–220 nm, comparing peak area to a certified reference standard. |
| Identity | FT-IR Spectroscopy | Confirms molecular structure by matching characteristic absorption bands (e.g., carbamate C=O, ester C=O, N–H) to reference spectrum. |
| Chiral Purity | Chiral HPLC | Resolves enantiomers using a chiral stationary phase; quantifies L-leucine-derived enantiomeric excess via retention time and peak area comparison. |
| Residual Solvents | GC-FID | Detects and quantifies volatile organic solvents (e.g., DCM, THF, MeOH) using gas chromatography with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration | Determines trace water content via coulometric or volumetric titration based on iodine–sulfur dioxide redox reaction in pyridine/methanol medium. |
| Heavy Metals | ICP-MS | Quantifies trace elemental impurities (e.g., Pb, Cd, Ni, Pd) after acid digestion by measuring isotopic mass-to-charge ratios with high sensitivity and multi-element capability. |
| Residual Palladium | ICP-OES | Measures palladium residue from coupling catalysts by plasma excitation and optical emission detection at characteristic wavelengths (e.g., 340.458 nm). |
| Related Substances | HPLC-UV (Gradient) | Separates and quantifies structurally related impurities (e.g., Boc-Leu-OH, Boc-Leu-OSu hydrolysis/decomposition products) using gradient elution and UV detection. |
| Melting Point | Capillary Melting Point Apparatus | Determines thermal transition range by observing solid-to-liquid phase change under controlled heating; confirms batch consistency and absence of eutectic impurities. |
| Appearance & Color | Visual Inspection / APHA Color Scale | Assesses physical state (white to off-white crystalline powder) and color intensity against standardized APHA scale in solution (e.g., 1% w/v in acetonitrile). |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.5% (by LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Melting Point | 72-76°C |
| Optical Rotation | -43 to -41° (c=1, in CHCl3) |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=20 ppm |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.