China Factory Direct
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| CAS number | 3392-10-7 |
| Product name | BOC-PRO-OSU |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Solid-phase protection and coupling of L-proline residues in peptide synthesis | Used as an active ester reagent in solid-phase peptide synthesis (SPPS) to N-acylate resin-bound amino components, enabling efficient, low-racemization incorporation of BOC-protected L-proline |
| Biochemistry | Protein modification and construction of crosslinking probes | Applied for selective labeling of proteins or antibodies containing primary amines; reacts with lysine ε-amino groups via NHS ester chemistry to introduce a BOC-proline spacer arm, facilitating subsequent deprotection and functionalization |
| Materials Science | Amino acid grafting onto functionalized polymeric carriers (e.g., PEG derivatives, microspheres) | Reacted with amine-functionalized polymers under mild alkaline conditions (pH 8.0–9.0, in DMF or DMSO solvent) to construct chiral proline-containing, biocompatible surfaces |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 220 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time relative to reference standards or threshold reporting. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., DMF, THF, ethyl acetate) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine-based reagent to determine trace water content based on stoichiometric reaction with water. |
| Optical Rotation | [alpha]D Measurement | Measurement of specific optical rotation using a polarimeter at 20 C and sodium D-line (589 nm) to confirm chiral integrity and enantiomeric purity. |
| Heavy Metals | ICP-MS | Quantitative multi-element analysis after acid digestion; detection of Pb, Cd, Hg, As, and other regulated metals at sub-ppb levels. |
| Chloride Content | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column with conductivity detection; calibrated against NaCl standards. |
| Residual Catalyst (Pd) | ICP-OES | Inductively coupled plasma optical emission spectroscopy after microwave-assisted digestion to quantify palladium residues from coupling synthesis steps. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement using controlled heating rate; confirms identity and crystallinity by comparison to literature value. |
| Appearance | Visual Inspection | Assessment of physical form (white to off-white crystalline powder) and absence of visible particulates or discoloration under controlled lighting. |
| Loss on Drying | Gravimetric Analysis | Weight loss measured after drying under vacuum at 60 C for 2 hours; indicates volatile content including residual solvents and moisture. |
| pH of Solution (1% w/v) | pH Meter | Measurement of aqueous suspension pH using calibrated electrode; reflects acidic/basic impurities affecting stability and handling. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 75–79°C |
| Optical Rotation | +24.0 to +26.0° (c=1, in DMF) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.