tert-Butoxycarbonyl-L-valine N-hydroxysuccinimide ester Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 3392-12-9 |
| Product name | tert-Butoxycarbonyl-L-valine N-hydroxysuccinimide ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for tert-Butoxycarbonyl-L-valine N-hydroxysuccinimide ester
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk tert-Butoxycarbonyl-L-valine N-hydroxysuccinimide ester Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of tert-Butoxycarbonyl-L-valine N-hydroxysuccinimide ester
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Activated ester reagent for peptide synthesis, used to introduce Boc-protected L-valine residues | Coupled with amine components to form amide bonds in solid-phase or solution-phase peptide synthesis |
| Biochemistry | Protein modification and bioconjugation reactions to construct functional molecules containing valine structures | Reacts with primary amines under mild conditions to yield stable amide bonds |
| Organic Synthesis | Chiral building block for constructing complex natural product or drug molecule scaffolds | Selective acylation reaction preserving the Boc protecting group for subsequent deprotection |
Manufacturing Quality Control of tert-Butoxycarbonyl-L-valine N-hydroxysuccinimide ester
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 210 nm, comparing peak area against a certified reference standard. |
| Chiral Purity | Chiral HPLC | Enantiomeric excess assessment using a chiral stationary phase and UV detection, distinguishing L- and D-enantiomers by retention time. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration based on the stoichiometric reaction of iodine with water in pyridine/methanol medium. |
| Residual Solvents | GC-FID | Identification and quantification of common solvents (e.g., DMF, THF, ethyl acetate) using gas chromatography with flame ionization detection. |
| Heavy Metals | ICP-OES | Multi-element detection of Pb, Cd, Hg, As, and others after acid digestion, based on atomic emission intensity at characteristic wavelengths. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column and suppressed conductivity detection. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., Boc-Val-OH, NHS, di-Boc derivatives) via gradient HPLC-UV. |
| Appearance | Visual Inspection | Assessment of physical state, color, and homogeneity against defined reference standards under controlled lighting conditions. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid-to-liquid phase transition occurs, using calibrated capillary apparatus. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral molecules in solution at specified concentration and wavelength. |
| Loss on Drying | Gravimetric Method | Mass loss measured after drying under controlled temperature and vacuum, indicating volatile content including residual solvents and moisture. |
| pH of Solution | Potentiometric pH Measurement | Determination of hydrogen ion activity in aqueous suspension using calibrated glass electrode and pH meter. |
Technical Specifications of tert-Butoxycarbonyl-L-valine N-hydroxysuccinimide ester
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Optical Rotation | -38° ± 2° (c=1, in CHCl3) |
| Melting Point | 75–79°C |
| Identification (NMR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of tert-Butoxycarbonyl-L-valine N-hydroxysuccinimide ester
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of tert-Butoxycarbonyl-L-valine N-hydroxysuccinimide ester
Safety Information of tert-Butoxycarbonyl-L-valine N-hydroxysuccinimide ester
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of tert-Butoxycarbonyl-L-valine N-hydroxysuccinimide ester
Industrial tert-Butoxycarbonyl-L-valine N-hydroxysuccinimide ester Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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