China Factory Direct
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| CAS number | 341-23-1 |
| Product name | 4-FLUORO (1H)INDAZOLE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a pharmaceutical intermediate in the synthesis of compounds exhibiting antitumor, anti-inflammatory, or central nervous system activity | Introduced as a 4-fluoro-1H-indazole structural motif into multistep organic syntheses via fluorination, cyclization, or coupling reactions |
| Agrochemicals | Employed as a lead compound for developing novel insecticides or fungicides | Applied as a heterocyclic scaffold to construct biologically active molecular structures through substitution or condensation reactions |
| Chemical Research | Utilized as a functionalized heterocyclic building block in organic synthesis for exploring new drug candidates or material properties | Modified structurally via metal-catalyzed coupling (e.g., Suzuki, Buchwald–Hartwig), nucleophilic substitution, or rearrangement reactions |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 254 nm, based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient HPLC-UV; identification via retention time matching and threshold-based reporting. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., acetone, methanol, toluene) by gas chromatography with flame ionization detection using headspace sampling. |
| Water Content | Karl Fischer Titration | Determines trace water by coulometric or volumetric titration with iodine-based reagent, based on stoichiometric electrochemical reaction. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pb, Cd, Ni, As) after acid digestion using inductively coupled plasma mass spectrometry with isotope dilution. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction and filtration. |
| Sulfated Ash | Gravimetric Analysis | Measures inorganic residue after controlled combustion with sulfuric acid treatment and high-temperature incineration to constant weight. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid phase transition using calibrated capillary tube method per USP <741>. |
| Optical Rotation | Polarimetry | Measures specific rotation using sodium D-line light source to assess chiral purity and absence of racemization. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry powder size distribution by measuring angular scattering pattern of laser beam passing through dispersed sample. |
| pH of Aqueous Suspension | pH Meter | Measures hydrogen ion activity in a defined suspension (e.g., 1% w/v in water) using calibrated glass electrode pH meter. |
| Microbial Contamination | Membrane Filtration | Detects aerobic microorganisms by filtering sample solution, culturing on soybean-casein digest agar, and counting colony-forming units. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.5% (by LC-MS) |
| Melting Point | 148–152 °C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.