Phosphonoformic acid trisodium salt hexahydrate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 34156-56-4 |
| Product name | Phosphonoformic acid trisodium salt hexahydrate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Phosphonoformic acid trisodium salt hexahydrate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Phosphonoformic acid trisodium salt hexahydrate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Phosphonoformic acid trisodium salt hexahydrate
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Antiviral agent for the treatment of cytomegalovirus infection | Administered via intravenous injection |
| Pharmaceutical Industry | Treatment of acyclovir-resistant herpes simplex virus infection | Administered via intravenous infusion or topical formulation |
| Pharmaceutical Industry | Adjunctive therapy for viral infections in immunocompromised patients | Used in combination with other antiviral agents |
| Pharmaceutical R&D | Research tool as a viral DNA polymerase inhibitor | Applied in in vitro cell-based assays and mechanistic studies |
Manufacturing Quality Control of Phosphonoformic acid trisodium salt hexahydrate
| Test Item | Common Test Methods | Method Overview |
|---|---|---|
| Identification | Infrared Spectroscopy (IR) | Determine the infrared absorption spectrum of the sample and compare it with the standard spectrum to confirm molecular structural characteristics. |
| Sodium Ion Flame Test or Atomic Absorption Spectroscopy (AAS) | Confirm the presence of sodium ions qualitatively based on the characteristic yellow flame color of sodium or using atomic absorption spectroscopy. | |
| Phosphorus Element Qualitative Test | Confirm the presence of phosphate or phosphonate groups using colorimetric reactions such as ammonium molybdate. | |
| Assay | Complexometric Titration (EDTA Titration) | Use EDTA's ability to form complexes with metal ions to indirectly determine the content of foscarnet sodium (requires additional validation). |
| High-Performance Liquid Chromatography (HPLC) | Use reversed-phase HPLC with appropriate mobile phase and detection wavelength (e.g., 210 nm), and quantify the main component using external standard method. | |
| pH Value | pH Meter Method | Prepare a solution of the test sample at specified concentration and measure its pH using a calibrated pH meter; typically within the range of 6.5–8.5. |
| Water Content | Karl Fischer Method | Determine water content in the sample using volumetric or coulometric Karl Fischer titration, applicable for controlling both crystalline and adsorbed water. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Use gradient or isocratic elution to separate and detect potential degradation products or process impurities, quantifying by area normalization or external standard method. |
| Heavy Metals | Thioacetamide Method or Atomic Absorption Spectroscopy | Perform heavy metal limit testing according to pharmacopoeial general chapters, usually requiring ≤20 ppm. |
| Solution Clarity and Color | Visual Turbidity/Color Comparison Method | Compare the sample solution with standard turbidity/color solutions visually to assess whether clarity and color meet specifications. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Constant Temperature Drying Method | Dry the sample at a specified temperature (e.g., 105°C) to constant weight and measure weight loss, reflecting moisture and volatile content. |
| Residual Solvents | Gas Chromatography (GC) | Use headspace or direct injection GC to detect organic solvents possibly remaining from synthesis or purification processes. |
| Microbial Limits | Microbiological Culture Method | Perform testing for aerobic bacteria, molds/yeasts, and specified microorganisms according to the *Chinese Pharmacopoeia* or relevant regulations. |
| Iron Chelating Capacity (Functional) | Spectrophotometry or Titration (Optional) | Foscarnet has the ability to chelate metal ions; its activity can be evaluated by measuring absorbance changes after complexation with Fe³⁺ (non-mandatory test). |
Technical Specifications of Phosphonoformic acid trisodium salt hexahydrate
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
| Identification (NMR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Phosphonoformic acid trisodium salt hexahydrate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Phosphonoformic acid trisodium salt hexahydrate
Safety Information of Phosphonoformic acid trisodium salt hexahydrate
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Phosphonoformic acid trisodium salt hexahydrate
Industrial Phosphonoformic acid trisodium salt hexahydrate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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