5-FLUOROGRAMINE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 343-90-8 |
| Product name | 5-FLUOROGRAMINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5-FLUOROGRAMINE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-FLUOROGRAMINE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-FLUOROGRAMINE
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing antitumor agents (e.g., fluorouracil derivatives) and 5-HT receptor modulators | Undergoes substitution with halogenating reagents (e.g., NBS) under basic conditions, or Pd-catalyzed cross-coupling to construct C–F bonds; commonly serves as a fluorinated precursor for indole-based scaffolds in multistep syntheses |
| Agrochemicals | Potential structural motif for plant growth regulators and fungicidal active ingredients | Vilsmeier–Haack formylation introduces an aldehyde group, followed by oxidation/condensation to construct heterocyclic agrochemical molecules |
| Organic Synthesis | Fluorinated heterocyclic building block for constructing biologically active fluorinated heterocycles such as fluorinated indoles and β-carbolines | Acts as a chiral auxiliary in asymmetric alkylation; or undergoes diazotization–denitrogenative fluorination (e.g., using Selectfluor) for regioselective fluorination at the C5 position |
Manufacturing Quality Control of 5-FLUOROGRAMINE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-DAD | Separation and identification of impurities using gradient HPLC with diode-array detection; impurities quantified relative to main peak. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify common organic solvents (e.g., methanol, acetone, ethyl acetate) based on retention time and peak area. |
| Water Content | Karl Fischer Titration | Volumetric titration using iodine, sulfur dioxide, and base in methanol medium; water reacts stoichiometrically to determine moisture content. |
| Heavy Metals | ICP-MS | Inductively coupled plasma mass spectrometry for simultaneous quantification of toxic elements (e.g., Pb, Cd, Hg, As) at trace levels. |
| Chloride Impurity | Ion Chromatography | Separation of anions on an ion-exchange column with suppressed conductivity detection; chloride quantified via calibration curve. |
| Sulfated Ash | Gravimetric Analysis | Ignition of sample at 700-800 C followed by weighing of residual inorganic ash after treatment with sulfuric acid. |
| Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral molecules in solution at specified concentration and wavelength (e.g., sodium D line). |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed as the temperature range over which solid transforms to liquid, determined by controlled heating of capillary-packed sample. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determination of hydrogen ion activity using calibrated glass electrode and reference electrode in a saturated aqueous suspension. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity patterns from dispersed particles to calculate size distribution based on Mie theory. |
| Microbial Limits | Membrane Filtration and Plate Count | Enumeration of aerobic microorganisms and detection of specified pathogens (e.g., E. coli, S. aureus) following USP <61> and <62>. |
Technical Specifications of 5-FLUOROGRAMINE
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 124–128°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
| Optical Rotation | -15° to -25° (c=1, in methanol) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5-FLUOROGRAMINE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5-FLUOROGRAMINE
Packaging of 5-FLUOROGRAMINE
Industrial 5-FLUOROGRAMINE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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