azetidine-3-carboxylic acid methyl ester Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 343238-58-4 |
| Product name | azetidine-3-carboxylic acid methyl ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for azetidine-3-carboxylic acid methyl ester
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk azetidine-3-carboxylic acid methyl ester Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of azetidine-3-carboxylic acid methyl ester
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Organic synthesis intermediate | Used to construct nitrogen-containing heterocyclic compounds; employed in coupling and hydrolysis reactions within multistep synthesis routes to prepare biologically active drug molecules |
| Fine chemicals | Functionalization reagent | Applied as an azetidine derivative to introduce azetidine structural units during targeted functional group modification processes |
| Biopharmaceuticals | Drug candidate synthesis | Utilized as a key intermediate in new drug discovery for synthesizing protease inhibitors or receptor modulators |
Manufacturing Quality Control of azetidine-3-carboxylic acid methyl ester
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 210 nm, calibrated against certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and threshold limits. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify methanol, dichloromethane, and other process solvents per ICH Q3C. |
| Water Content | Karl Fischer Titration | Volumetric titration using iodine-based reagent to determine water content based on stoichiometric redox reaction. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and Ni after acid digestion, per USP <232> and ICH Q3D. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using silver indicator electrode; endpoint detected by potential change. |
| pH of Aqueous Solution | pH Meter Measurement | Direct measurement of 1% w/v aqueous solution using calibrated pH meter with glass electrode. |
| Residue on Ignition | Gravimetric Analysis | Ignition at 700-800 C followed by weighing of inorganic residue to assess inorganic ash content. |
| Particle Size Distribution | Laser Diffraction | Dry dispersion and size analysis via laser diffraction to determine D10, D50, D90 values. |
| Bulk Density | USP <616> Tap Density Test | Measurement of untapped and tapped density using standardized cylinder and mechanical tapping apparatus. |
| Microbial Contamination | Membrane Filtration | Filtration of sample solution followed by incubation on soybean-casein digest agar and sabouraud dextrose agar. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light source to confirm chiral integrity and enantiomeric purity. |
Technical Specifications of azetidine-3-carboxylic acid methyl ester
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142-146°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of azetidine-3-carboxylic acid methyl ester
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Safety Information of azetidine-3-carboxylic acid methyl ester
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of azetidine-3-carboxylic acid methyl ester
Industrial azetidine-3-carboxylic acid methyl ester Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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