4-METHYL-6-CHLORO PYRIMIDINE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 3435-25-4 |
| Product name | 4-METHYL-6-CHLORO PYRIMIDINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-METHYL-6-CHLORO PYRIMIDINE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-METHYL-6-CHLORO PYRIMIDINE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-METHYL-6-CHLORO PYRIMIDINE
| Industry | Application | Process |
|---|---|---|
| Pesticides | Key intermediate for synthesizing sulfonylurea herbicides (e.g., bispyribac-sodium, pyrazosulfuron-ethyl) | Used to construct the sulfonylurea core via condensation and cyclization with aniline derivatives |
| Pharmaceuticals | Structural building block for anticancer agents (e.g., gemcitabine derivatives) and kinase inhibitors | Serves as a pyrimidine ring modification precursor, enabling nucleophilic substitution or coupling reactions to introduce methyl or chloro substituents |
| Dyes | Heterocyclic building block for reactive dyes and fluorescent brighteners | Integrated into chromophore systems via amination or alkoxylation at the chlorine site |
Manufacturing Quality Control of 4-METHYL-6-CHLORO PYRIMIDINE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 240-260 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-DAD | Separation and identification of impurities using HPLC coupled with diode-array detection; relative retention times and UV spectra support structural assignment. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents (e.g., methanol, acetone, toluene) based on calibrated response factors. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent; water reacts stoichiometrically with iodine and sulfur dioxide in pyridine/methanol medium. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, Hg, As) after acid digestion, using isotopic detection with high sensitivity and low detection limits. |
| Chloride Ion Impurity | Ion Chromatography | Separation of anions on an ion-exchange column with suppressed conductivity detection; chloride is quantified against calibration standards. |
| Sulfated Ash | Gravimetric Analysis | Sample ignited at 500-600 C after sulfuric acid treatment; residual inorganic ash is weighed to determine total inorganic residue. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or via automated optical detection as solid transforms to liquid; correlates with crystallinity and purity. |
| Appearance | Visual Inspection | Assessment under controlled white light against a white/black background for color, clarity, and presence of particulates or foreign matter. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light by chiral impurities or enantiomeric contaminants; reported as degrees per dm per g/mL. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity versus angle to calculate volume-based particle size distribution in dry or dispersed state. |
| pH of Aqueous Suspension | pH Meter | Measurement of hydrogen ion activity in a standardized suspension (e.g., 1% w/v in water) using calibrated glass electrode pH meter. |
Technical Specifications of 4-METHYL-6-CHLORO PYRIMIDINE
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 78-82°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-METHYL-6-CHLORO PYRIMIDINE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-METHYL-6-CHLORO PYRIMIDINE
Packaging of 4-METHYL-6-CHLORO PYRIMIDINE
Industrial 4-METHYL-6-CHLORO PYRIMIDINE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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