D-Proline Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 344-25-2 |
| Product name | D-Proline |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeIndustrial GradeSpecialty GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for D-Proline
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk D-Proline Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of D-Proline
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Chiral auxiliaries and ligands for chiral catalysts in the synthesis of chiral drugs (e.g., antiviral agents, antihypertensives) | Applied in asymmetric synthesis, chiral resolution, and asymmetric hydrogenation |
| Fine Chemicals | Chiral intermediates for preparing other proline derivatives and chiral ligands | Applied in organic synthesis, solid-phase peptide synthesis, and N-protection/deprotection reactions |
| Agricultural Chemicals | Active chiral ingredients or key intermediates for agrochemicals (e.g., chiral insecticides, fungicides) | Applied in chiral synthesis, asymmetric cyclization, and side-chain modification |
| Food & Feed Additives | Nutritional fortifier and flavor enhancer (as the enantiomer of L-proline; certain applications are subject to regulatory restrictions) | Applied in fermentation process modulation and compound blending (compliance with applicable regulations required) |
| Biochemical Research | Additive in cell culture, probe for protein structural studies, and tool for enzyme inhibitor research | Applied in in vitro enzymology assays, cell culture medium preparation, and X-ray crystallography analysis |
Manufacturing Quality Control of D-Proline
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Identification | Infrared Spectroscopy (IR) | Compare the sample's infrared absorption spectrum with the standard D-proline reference spectrum to confirm consistency of characteristic molecular absorption peaks. |
| Nuclear Magnetic Resonance Spectroscopy (NMR) | Analyze characteristic chemical shifts and coupling constants using ¹H-NMR or ¹³C-NMR to confirm the stereochemistry and chemical structure of D-proline. | |
| Assay | High-Performance Liquid Chromatography (HPLC) | Quantify D-proline content using reversed-phase HPLC or ion-exchange chromatography, coupled with UV or evaporative light scattering detection. |
| Amino Acid Automatic Analyzer | Separate amino acids via cation-exchange chromatography followed by derivatization and detection; specifically designed for precise quantification of amino acid components including D-proline. | |
| Optical Purity / Enantiomeric Purity | Chiral High-Performance Liquid Chromatography (Chiral HPLC) | Use chiral stationary phase columns to separate D- and L-proline, evaluate enantiomeric impurity levels, and determine optical purity. |
| Capillary Electrophoresis (CE) | Separate D/L-proline enantiomers using chiral selectors (e.g., cyclodextrins); high sensitivity suitable for trace enantiomer detection. | |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Loss on Drying Method | Heat the sample under specified conditions and measure mass loss to assess residual moisture or volatile components. |
| Residue on Ignition | Sulfated Ash Method | Incinerate the sample at high temperature and weigh the residual ash to determine inorganic impurity content. |
| Solution Clarity and Color | Visual Comparison or UV-Visible Spectrophotometry | Prepare a solution of the sample and compare it with standard turbidity or color reference solutions to assess clarity and color compliance. |
| Related Substances (Impurities) | HPLC-UV or LC-MS | Detect organic impurities potentially generated during synthesis or degradation, such as other amino acids or by-products, to evaluate purity. |
| pH Value | pH Meter Method | Prepare a specified concentration aqueous solution of D-proline and measure its acidity or alkalinity using a calibrated pH meter. |
| Microbial Limits | Microbial Limit Test | Perform assays as per pharmacopeial requirements to determine total aerobic microbial count, mold and yeast counts, and test for specified control organisms (e.g., Escherichia coli). |
Technical Specifications of D-Proline
| Test Item | Specification |
|---|---|
| Appearance | White to almost white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 207.0 to 211.0 °C |
| Optical Rotation | +83.0 to +87.0 ° (c=1, H2O) |
| Total Impurities | <=1.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of D-Proline
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of D-Proline
Packaging of D-Proline
Industrial D-Proline Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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