2-AMINO-4-TRIFLUOROMETHYL-THIAZOLE-5-CARBOXYLIC ACID ETHYL ESTER Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 344-72-9 |
| Product name | 2-AMINO-4-TRIFLUOROMETHYL-THIAZOLE-5-CARBOXYLIC ACID ETHYL ESTER |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 344-72-9
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 344-72-9 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 344-72-9
| Industry | Application | Process |
|---|---|---|
| Pesticides | Insecticide intermediate | Serves as a structural building block for synthesizing thiazole-based insecticides (e.g., thiamethoxam) via cyclization and substitution reactions to construct the thiazole ring core |
| Pharmaceuticals | Antimicrobial drug intermediate | Acts as a precursor for modifying the thiazole ring in heterocyclic drug molecules, enabling synthesis of bioactive brominated thiazole derivatives |
| Organic Synthesis | Multifunctional organic synthesis building block | Used to prepare heterocyclic compounds bearing both tribromomethyl and amino functional groups; commonly employed in nucleophilic substitution, reductive amination, and metal-catalyzed cross-coupling reactions |
Manufacturing Quality Control of 344-72-9
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV/DAD | Separation and identification of impurities using gradient HPLC with diode-array detection; qualification/quantification based on relative response factors or reference standards. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify common solvents (e.g., ethanol, dichloromethane) per ICH Q3C guidelines. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic elements (Pb, Cd, Hg, As) after acid digestion, achieving sub-ppb sensitivity and compliance with ICH Q3D. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with sample moisture. |
| Residue on Ignition | Gravimetric Analysis | Weight loss on ignition at 700–800 °C to determine inorganic ash content after complete organic matrix combustion. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and quantification of chloride ions using anion-exchange column with suppressed conductivity detection. |
| Optical Rotation | [α]D Measurement | Specific rotation determination at 20 °C using sodium D-line (589 nm) to confirm chiral integrity and absence of racemization. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition analysis by controlled heating to verify identity and crystallinity consistency per pharmacopeial standards. |
| Particle Size Distribution | Laser Diffraction | Dry or wet dispersion followed by light scattering analysis to characterize bulk handling and dissolution behavior. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | pH determination of a standardized suspension (e.g., 1% w/v in water) using calibrated pH electrode to assess acid/base character and hydrolytic stability. |
Technical Specifications of 344-72-9
| Test Item | Specification |
|---|---|
| Appearance | Off-white to yellow solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.3% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 344-72-9
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 344-72-9
Packaging of 344-72-9
Industrial 344-72-9 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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