China Factory Direct
|
|
| CAS number | 3459-92-5 |
| Product name | 3459-92-5 |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Used as a benzyl protecting group in the synthesis of antiviral agents (e.g., adefovir dipivoxil) and anticancer drugs | Reacts with hydroxyl-containing compounds under basic conditions to introduce a benzyl carbonate protecting group, which can subsequently be removed via hydrogenolysis |
| Organic Synthesis | Acts as a benzylating reagent for selective protection of functional groups such as alcohols, phenols, and amines | Undergoes O-alkylation with alcohols or phenols in the presence of a base (e.g., NaH, K2CO3); reacts with amines to form N-benzyl carbamate derivatives |
| Polymer Chemistry | Applied as a crosslinking agent or functional monomer to prepare degradable polymers containing benzyl carbonate moieties | Participates in condensation or ring-opening polymerization; the resulting polymers undergo degradation under acidic or reducing conditions to release CO2 and toluene |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detection | Quantitative determination based on peak area comparison against a certified reference standard using a non-polar capillary column. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration where iodine is generated in situ to react stoichiometrically with water in the sample. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Measurement of non-volatile inorganic residue after high-temperature ashing at 700-800 C in a muffle furnace. |
| Chloride Impurity | Ion Chromatography (IC) with Conductivity Detection | Separation and quantification of chloride ions using an anion-exchange column and suppressed conductivity detection. |
| Heavy Metals (as Pb) | Atomic Absorption Spectroscopy (AAS) after acid digestion | Quantification of total heavy metals by flame or graphite furnace AAS following microwave-assisted nitric acid digestion. |
| Acid Value | Acid-Base Titration with NaOH and phenolphthalein indicator | Neutralization of acidic impurities (e.g., benzoic acid) with standardized sodium hydroxide solution. |
| Color (APHA) | Visual Comparison or Spectrophotometric Measurement at 455 nm | Evaluation of yellowness intensity by matching sample absorbance at 455 nm to APHA color scale standards. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid phase transition temperature range using calibrated capillary tube method per USP <741>. |
| Residual Solvents (e.g., toluene, methanol) | Headspace Gas Chromatography (HS-GC) with FID | Extraction and quantification of volatile organic solvents via equilibrium headspace sampling and GC separation. |
| Sulfated Ash | Gravimetric Analysis (Sulfuric Acid Ashing) | Determination of inorganic sulfate-derived residue after wet ashing with sulfuric acid followed by ignition. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light caused by chiral impurities or enantiomeric excess in solution. |
| Particle Size Distribution | Laser Diffraction Particle Size Analysis | Analysis of particle size based on angular variation of laser light scattering intensity from dispersed sample. |
| Test Item | Specification |
|---|---|
| Appearance | White to almost white powder or lumps |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 72–76°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.