TAUROCHOLIC ACID SODIUM SALT HYDRATE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 345909-26-4 |
| Product name | TAUROCHOLIC ACID SODIUM SALT HYDRATE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for TAUROCHOLIC ACID SODIUM SALT HYDRATE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk TAUROCHOLIC ACID SODIUM SALT HYDRATE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of TAUROCHOLIC ACID SODIUM SALT HYDRATE
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | As a bile acid derivative in drug delivery systems to enhance solubility and oral bioavailability of poorly water-soluble drugs | Used as a surfactant or solubilizer in formulations, combined with active pharmaceutical ingredients via co-precipitation, microemulsion, or micellar encapsulation |
| Pharmaceuticals | Clinical research for cholestatic disorders (e.g., primary biliary cholangitis) | Administered orally as an endogenous bile acid replacement therapy in clinical trials to modulate FXR receptor signaling |
| Biochemical Research | Cell culture additive to maintain differentiated phenotypes of hepatocytes or biliary epithelial cells | Added to specialized media (e.g., Williams’ E or HCM-1) at final concentrations of 10–100 μM, in combination with hormones and growth factors |
| Diagnostics | Internal standard for mass spectrometry-based quantification of bile acid profiles in human serum or bile | Isotope-labeled (e.g., d4-glycocholic acid sodium salt) and co-extracted with samples, followed by derivatization and detection using LC-MS/MS in multiple reaction monitoring (MRM) mode |
Manufacturing Quality Control of TAUROCHOLIC ACID SODIUM SALT HYDRATE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination based on peak area comparison with a certified reference standard using reversed-phase chromatography and UV detection at 200-210 nm. |
| Related Substances | HPLC-UV | Separation and quantification of structurally related impurities (e.g., unconjugated bile acids, degradation products) relative to main peak using gradient elution. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents (e.g., methanol, acetone, ethyl acetate) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration measuring water via iodine-sulfur dioxide reaction in pyridine-free reagent system. |
| Heavy Metals | ICP-MS | Multi-element quantitative analysis of toxic metals (Pb, Cd, Hg, As) after acid digestion, based on mass-to-charge ratio detection. |
| Sodium Content | Flame Photometry | Quantification of sodium ions by measuring characteristic emission intensity at 589 nm in an air-acetylene flame. |
| pH (1% aqueous solution) | Potentiometric Titration | Measurement of hydrogen ion activity using calibrated glass electrode in aqueous solution at specified concentration and temperature. |
| Specific Optical Rotation | Polarimetry | Determination of chiral purity by measuring the angle of rotation of plane-polarized light at 589 nm using a sodium lamp. |
| Residue on Ignition | Gravimetric Analysis | Quantification of inorganic ash content after controlled high-temperature incineration and weighing of residual non-volatile matter. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic mesophilic bacteria and detection of specified pathogens (e.g., E. coli, Salmonella) following USP <61> and <62>. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder particle size via scattering pattern measurement of laser beam passed through dispersed sample. |
| Loss on Drying | Thermogravimetric Analysis | Determination of volatile content by measuring mass loss under controlled heating (105 C, 2 h) in a ventilated oven. |
Technical Specifications of TAUROCHOLIC ACID SODIUM SALT HYDRATE
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Melting Point | 235-240°C (decomposes) |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
| Optical Rotation | -25° to -35° (c=1, in 0.1N NaOH) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of TAUROCHOLIC ACID SODIUM SALT HYDRATE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of TAUROCHOLIC ACID SODIUM SALT HYDRATE
Safety Information of TAUROCHOLIC ACID SODIUM SALT HYDRATE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of TAUROCHOLIC ACID SODIUM SALT HYDRATE
Industrial TAUROCHOLIC ACID SODIUM SALT HYDRATE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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