China Factory Direct
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| CAS number | 346-55-4 |
| Product name | 4-Chloro-7-(trifluoromethyl)quinoline |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | Intermediate for synthesizing insecticides and fungicides | Prepared via reaction of halogenated quinolines with trifluoromethylating reagents, for subsequent structural modification |
| Pharmaceuticals | Fluorinated heterocyclic scaffold for antiviral and anticancer drug synthesis | Key intermediate in nucleophilic substitution or coupling reactions to construct drug molecules |
| Dyes | Fluorinated aromatic component in high-performance dyes | Quinoline structure introduced via coupling reactions to enhance photostability and color fastness of dyes |
| Materials Science | Used in the preparation of organic semiconductors and optoelectronic materials | Electron-accepting unit in the synthesis of conjugated polymers |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 254 nm, based on peak area comparison against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; individual impurities reported relative to main peak using external standard or area normalization. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents by gas chromatography with flame ionization detection, using internal standard calibration. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine generated electrochemically to react stoichiometrically with water in the sample. |
| Heavy Metals | ICP-MS | Multi-element detection and quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, based on mass-to-charge ratio detection. |
| Chloride Ion Impurity | Ion Chromatography | Separation and quantification of chloride anions using suppressed conductivity detection after anion-exchange column separation. |
| Residue on Ignition | Gravimetric Analysis | Determination of inorganic ash content by ignition at 700-800 C followed by precise weighing of residual residue. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement via visual observation of solid-to-liquid phase change in a capillary tube under controlled heating rate. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity of bulk material against established reference standards under standardized lighting conditions. |
| Bulk Density | Tap Density Tester | Measurement of mass per unit volume after mechanical tapping of a known mass of powder in a calibrated cylinder. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity as a function of angle to determine particle size distribution based on Mie scattering theory. |
| Organic Volatile Impurities (OVI) | GC-MS | Targeted and non-targeted identification and quantification of volatile organic impurities using gas chromatography coupled with mass spectrometric detection. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (HPLC) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 124–128°C |
| Identification (NMR) | Conforms to reference standard |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.