China Factory Direct
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| CAS number | 34784-04-8 |
| Product name | 5-Bromoisoquinoline |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Intermediate for synthesizing antitumor, antibacterial, and antiviral drugs | Used as a key building block in transition metal-catalyzed cross-coupling reactions—such as Suzuki coupling and Heck reaction—to construct isoquinoline-based bioactive molecular scaffolds |
| Agrochemical R&D | Structural modification intermediate for novel insecticides and fungicides | Enables introduction of specific functional groups via nucleophilic substitution or metal-catalyzed reactions to optimize compound inhibition activity against target enzymes |
| Materials Science | Synthetic precursor for electron-transport materials in organic light-emitting diode (OLED) devices | Boronated or aminated to produce isoquinoline derivatives with high electron mobility, applied in emissive or electron-transport layers |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies 5-bromoisoquinoline by separation on a reversed-phase column and UV detection at ~254 nm, using external standard calibration. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., isomers, bromination by-products) via gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Separates and quantifies volatile organic solvents (e.g., toluene, DMF, methanol) using capillary GC with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines trace water by coulometric or volumetric titration with iodine-based reagent; based on stoichiometric reaction of water with iodine and sulfur dioxide. |
| Heavy Metals | ICP-MS | Measures trace metal contaminants (e.g., Pb, Cd, Ni, Cu) after acid digestion, using inductively coupled plasma mass spectrometry for multi-element detection. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column with suppressed conductivity detection. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid, indicating purity and identity via comparison to reference standard. |
| Loss on Drying | Gravimetric Analysis | Measures volatile content by weight loss after drying under controlled temperature and vacuum conditions. |
| Residue on Ignition | Gravimetric Analysis | Quantifies inorganic ash residue after high-temperature incineration of sample in a platinum crucible. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of visible particulates or discoloration against established visual specifications. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light to confirm chiral integrity (if applicable) and detect racemization or contamination. |
| pH of Aqueous Suspension | pH Meter | Determines acidity/basicity of a defined suspension in water or buffer, indicating acidic/basic impurities or degradation products. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 112–116°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.