China Factory Direct
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| CAS number | 348-27-6 |
| Product name | 2-Fluoro-4-hydroxybenzaldehyde |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Key pharmaceutical intermediate | Serves as a fluorinated benzaldehyde derivative for constructing active molecular scaffolds in anticancer, antifungal, and cardiovascular drugs |
| Pharmaceutical Chemicals | Active pharmaceutical ingredient (API) synthesis building block | Leverages dual functionality of hydroxyl and aldehyde groups to construct heterocyclic structures via aldol condensation, reductive amination, or nucleophilic substitution |
| Agrochemicals | Agrochemical intermediate | Used in synthesizing fluorinated benzoyl-based herbicides or insecticides, where the fluorine moiety modulates biological activity |
| Organic Synthesis | Synthesis of fluorinated aromatic fine chemicals | Converted into high-value fluorinated aromatic derivatives via etherification, halogenation, or coupling reactions |
| Materials Science | Functional monomer synthesis | Serves as a monomer for synthesizing fluorinated polyarylethers or specialty polymers, leveraging its rigidity and fluorine atoms to enhance material performance |
| Test Item | Common Test Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection Method | Observe the color, state (e.g., white to off-white crystalline or powder), and presence of foreign matter with the naked eye to determine if it meets quality standards. |
| Identification | Infrared Spectroscopy (IR) High-Performance Liquid Chromatography (HPLC) Proton Nuclear Magnetic Resonance (¹H NMR) |
IR: Measure the infrared absorption spectrum of the sample and compare it with standard spectra; HPLC: The retention time under specific chromatographic conditions matches that of the reference standard; ¹H NMR: Confirm molecular structure through characteristic chemical shifts. |
| Assay/Content Determination | High-Performance Liquid Chromatography (HPLC) | Use a reverse-phase C18 column with methanol-water or acetonitrile-water as the mobile phase. Employ a UV detector (typically at 254 nm or adjusted based on maximum absorption) for quantification using external standard or internal standard methods. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Use gradient or isocratic elution programs to separate and detect possible process impurities or degradation products. Quantify using area normalization or the main component self-reference method with correction factors. |
| Moisture | Karl Fischer Titration | Determine moisture content by reacting the sample with Karl Fischer reagent in a quantitative reaction. Use potentiometric or coulometric titration for accurate detection of trace amounts of water. |
| Melting Point | Capillary Melting Point Determination | Fill the sample into a melting point capillary tube and slowly heat it in a melting point apparatus. Record the temperature range from initial melting to complete melting and compare it with the standard value (approximately 106–110 °C). |
| Residual Solvents | Gas Chromatography (GC) | Use headspace injection or direct injection with an FID detector. Detect organic solvents (e.g., methanol, ethanol, dichloromethane) potentially remaining from the production process according to pharmacopoeia guidelines. |
| Ignition Residue/Total Ash | Gravimetric Method | Heat the sample at high temperatures (typically 700–800 °C) until constant weight is achieved. Weigh the residual inorganic material to evaluate the total amount of inorganic impurities. |
| pH Value (if applicable) | pH Meter Method | Prepare a solution of appropriate concentration in water or suitable solvent. Measure acidity or alkalinity using a calibrated pH meter to reflect free acidic or basic impurities. |
| Test Item | Specification |
|---|---|
| Appearance | Beige powder |
| Purity | >=98.0% (GC) |
| Melting Point | 72-76°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.