China Factory Direct
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| CAS number | 348-57-2 |
| Product name | 1-Bromo-2,4-difluorobenzene |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a synthetic intermediate in the preparation of pharmaceutical compounds, including fluorinated arylamine-based antidepressants and antipsychotics | Fluorinated aryl groups are introduced via nucleophilic substitution, Suzuki coupling, or Buchwald–Hartwig amination |
| Agrochemicals | Used to synthesize fluorinated active ingredients, such as herbicides and insecticides | Molecular frameworks are constructed via Grignard reactions, halogen–metal exchange, or transition metal-catalyzed coupling |
| Materials Science | Employed as a precursor for liquid crystal monomers or organic optoelectronic materials | Conjugated systems are assembled using palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) |
| Fine Chemicals | Used to synthesize fluorinated fine chemicals with high added value, including fragrances and dyes | Selective functional group transformations are performed by leveraging the directed reactivity of the bromine and fluorine substituents |
| Test Item | Common Test Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color and state of the sample under natural light or standard illumination to determine if it is a colorless to pale yellow transparent liquid, and check for turbidity, sediment, or impurities. |
| Assay/Purity | Gas Chromatography (GC) | Use a capillary gas chromatograph to identify components by retention time and quantify the main component using peak area normalization or external standard method. Purity is typically required to be ≥99%. |
| Impurity Analysis | Gas Chromatography-Mass Spectrometry (GC-MS) | Combine the separation capability of GC with the structural identification power of MS to detect and identify potential organic impurities (e.g., isomers, unreacted starting materials). |
| Moisture Content | Karl Fischer Titration | Utilize the quantitative reaction of iodine with sulfur dioxide in methanol with water, and determine trace moisture content by coulometric or volumetric titration. Suitable for low-level moisture detection. |
| Bromine Content | Ion Chromatography (IC) or Elemental Analysis | Digest the sample and measure bromide ion concentration to verify whether bromine content meets theoretical values; alternatively, use a CHBr analyzer for elemental analysis. |
| Fluorine Content (Total or Organic Fluorine) | Ion-Selective Electrode Method or Elemental Analysis | Measure fluoride ion concentration released after alkali fusion or oxygen flask combustion, or directly determine C, H, Br, and F content using an elemental analyzer. |
| Residual Solvents | Gas Chromatography (GC) | In accordance with ICH guidelines, detect organic solvents possibly remaining from manufacturing (e.g., toluene, ethanol, dichloromethane) using headspace sampling. |
| Density | Density Meter or Pycnometer Method | Measure liquid density at a specified temperature (e.g., 20°C) using a densitometer or pycnometer to assist in assessing consistency of the substance. |
| Refractive Index | Abbe Refractometer Method | Measure refractive index (n20D) at standard temperature (e.g., 20°C), used as a physical constant for identification and purity assessment. |
| Boiling Point/Boiling Range | Distillation Method or Differential Scanning Calorimetry (DSC) | Determine the boiling range of the sample to assess volatility and purity; DSC can be used to measure phase transition temperatures. |
| Test Item | Specification |
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| Appearance | Pale-yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Refractive Index (n20/D) | 1.530–1.534 |
| Relative Density (20°C/25°C) | 1.54–1.56 g/cm³ |
| Identification (NMR) | Consistent with structure |
| Odor | Characteristic aromatic odor |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.