China Factory Direct
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| CAS number | 348-64-1 |
| Product name | 2,4-DICHLORO-5-FLUOROANILINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | Key intermediate for synthesizing fungicides such as fludioxonil | Used to construct the active molecular scaffold via diazotization-hydrolysis, halogenation, and subsequent coupling or acylation with 2,4-dichloro-5-fluoroaniline |
| Pharmaceuticals | Aromatic amine building block for synthesizing anticancer and anti-inflammatory drug candidates | Serves as a starting material for introducing fluorinated aniline side chains; participates in palladium-catalyzed cross-coupling (e.g., Buchwald-Hartwig amination) or reductive alkylation |
| Dyes | Weather-resistant intermediate for synthesizing high-performance azo and fluorescent dyes | After diazotization, coupled with phenols or aromatic amines; fluorine/chlorine co-substituents are introduced to enhance photostability and color fastness |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reversed-phase HPLC with UV detection at ~254 nm, comparing peak area against a certified reference standard. |
| Related Substances (Impurities) | HPLC-UV or GC-FID | Separation and quantification of structurally related impurities (e.g., isomers, residual precursors, dehalogenated by-products) using gradient HPLC or capillary GC. |
| Residual Solvents | GC-FID or GC-MS | Headspace GC analysis to identify and quantify volatile organic solvents (e.g., toluene, methanol, DMF) based on retention time and calibration curves. |
| Moisture Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine water content via stoichiometric reaction with iodine and sulfur dioxide. |
| Heavy Metals (as Pb) | ICP-OES or AAS | Digestion followed by quantification of total heavy metals (e.g., Pb, Cd, Ni, Fe) using atomic emission or absorption spectroscopy. |
| Chloride Ion (Cl⁻) | Ion Chromatography (IC) or Potentiometric Titration | Separation and quantification of ionic chloride using suppressed IC or direct titration with AgNO₃ and potentiometric endpoint detection. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid–liquid phase transition temperature using calibrated digital apparatus per USP <741>. |
| Appearance & Color | Visual Inspection / Hazen (APHA) Color Scale | Visual assessment of crystalline form and color intensity compared against platinum-cobalt standards. |
| Residue on Ignition | Gravimetric Analysis | Weighing residue after high-temperature ashing (700–800 °C) to determine inorganic non-volatile impurities. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light to confirm chiral purity (though compound is achiral, used to detect chiral contaminants). |
| Test Item | Specification |
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| Appearance | Brown solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 62–66°C |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.