5-Chloro-2,4-Difluoroaniline Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 348-65-2 |
| Product name | 5-Chloro-2,4-Difluoroaniline |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5-Chloro-2,4-Difluoroaniline
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-Chloro-2,4-Difluoroaniline Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-Chloro-2,4-Difluoroaniline
| Industry | Application | Process |
|---|---|---|
| Pesticides | Synthesis of herbicide and insecticide intermediates | Used as fluorinated aromatic amines in coupling or substitution reactions to prepare active pesticide ingredients |
| Pharmaceuticals | Pharmaceutical intermediate | Applied in the synthesis of biologically active fluorinated drug molecules, such as anti-inflammatory agents or central nervous system drugs |
| Dyes | Intermediate for organic pigments and dyes | Employed in diazotization reactions to produce azo dyes with specific molecular structures |
| Fine Chemicals | Synthesis of fluorinated aromatic amine derivatives | Serves as a key intermediate for constructing complex fluorinated arylamine structures, suitable for functional materials development |
Manufacturing Quality Control of 5-Chloro-2,4-Difluoroaniline
| Test Item | Common Test Methods | Method Summary |
|---|---|---|
| Appearance | Visual Inspection | Inspect the sample by eye for color, physical state (e.g., whether it is white to off-white crystalline powder), and presence of visible impurities to determine compliance with quality standards. |
| Identification | Infrared Spectroscopy (IR) High-Performance Liquid Chromatography (HPLC) |
IR: Record the infrared absorption spectrum of the sample and compare it with a reference spectrum to confirm structural characteristics; HPLC: Under specified chromatographic conditions, compare the retention time of the sample with that of the reference standard to confirm identity. |
| Assay | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with mobile phases such as methanol-water or acetonitrile-water, and detect using a UV detector (typically at around 254 nm). Quantify the main component using an external standard method to ensure purity meets requirements (e.g., ≥98.0%). |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Under the same or optimized chromatographic conditions as used in the assay, separate and detect potential process impurities and degradation products. Quantify using area normalization or a main component self-reference method with correction factors, to control limits for individual and total impurities. |
| Water Content | Karl Fischer Titration | Use Karl Fischer reagent to react quantitatively with water in the sample; determine water content by titration endpoint. Controls the degree of dryness (typically requires ≤0.5%). |
| Melting Point | Capillary Melting Point Method | Pack the sample into a melting point capillary tube and heat at a specified rate in a melting point apparatus. Record the temperature range from initial melting to complete melting to verify compliance with standard specifications (e.g., literature value approximately 73–76 °C). |
| Residual Solvents | Gas Chromatography (GC) | Use headspace or direct injection, with polar or non-polar capillary columns and FID detection to analyze organic solvents potentially remaining from manufacturing (e.g., toluene, dichloromethane). Limits are controlled according to ICH Q3C guidelines. |
| Residue on Ignition / Ash Content | Gravimetric Method | Ignite the sample at high temperature until constant weight is achieved, then weigh the remaining inorganic residue to assess inorganic impurity content (typically requires ≤0.1%). |
Technical Specifications of 5-Chloro-2,4-Difluoroaniline
| Test Item | Specification |
|---|---|
| Appearance | Pale-brown solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 45–49 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5-Chloro-2,4-Difluoroaniline
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5-Chloro-2,4-Difluoroaniline
Packaging of 5-Chloro-2,4-Difluoroaniline
Industrial 5-Chloro-2,4-Difluoroaniline Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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