China Factory Direct
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| CAS number | 348-67-4 |
| Product name | D-Methionine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeFood GradeCosmetic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Animal Feed Industry | Animal nutrition additive; supplements essential amino acids to support growth and feed conversion efficiency | Incorporated directly into compound feed formulations as a synthetic feed ingredient |
| Pharmaceutical Industry | Synthetic intermediate for drug manufacturing, particularly for sulfur-containing pharmaceuticals or nutritional supplements | Used in peptide synthesis, chiral drug construction, or as a precursor in chemical synthesis |
| Food Industry | Nutritional fortificant (limited use; L-methionine is typically preferred) | Added in trace amounts to specific functional foods or foods for special medical purposes |
| Cosmetics Industry | Antioxidant and skin-conditioning agent (research-stage or auxiliary application) | Formulated into skincare products to support keratin synthesis or scavenge free radicals via its sulfur-containing structure |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (D-Methionine Content) | Acid-Base Titration with HClO4 in non-aqueous medium | Quantifies D-methionine by potentiometric titration using perchloric acid in glacial acetic acid, based on protonation of the amino group. |
| Specific Optical Rotation | [a]D20 | Measures rotation of plane-polarized light at 20 C using sodium D-line; confirms chiral purity and identity of D-enantiomer. |
| Loss on Drying | Gravimetric Analysis (Thermogravimetry) | Determines volatile content by measuring mass loss after drying at 105 C under controlled conditions. |
| Residue on Ignition | Gravimetric Analysis (Sulfated Ash) | Quantifies inorganic impurities by incinerating sample to constant weight and weighing residual sulfate ash. |
| Heavy Metals (as Pb) | Atomic Absorption Spectroscopy (AAS) | Detects total heavy metals by flame or graphite furnace AAS after wet digestion and lead-specific measurement. |
| Chloride Impurity | Argentometric Titration (Mohr method) | Determines chloride ions by titration with silver nitrate using potassium chromate indicator. |
| Sulfate Impurity | Barium Sulfate Gravimetric Method | Precipitates sulfate as BaSO4 and determines content by weighing the dried precipitate. |
| Related Substances (Impurity Profile) | High-Performance Liquid Chromatography (HPLC) with UV detection | Separates and quantifies structurally related impurities (e.g., L-methionine, methionine sulfoxide, homocysteine) using reversed-phase C18 column and UV detection at 210 nm. |
| Water Content | Karl Fischer Coulometric Titration | Determines trace water by electrochemical generation of iodine and stoichiometric reaction with water in anhydrous medium. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Measures hydrogen ion activity in a 1% w/v aqueous solution using calibrated glass electrode. |
| Microbial Contamination | Membrane Filtration and Plate Count | Detects aerobic microorganisms by filtration, membrane transfer to nutrient agar, and colony enumeration after incubation. |
| Particle Size Distribution | Laser Diffraction Analysis | Determines particle size distribution by analyzing angular scattering pattern of laser beam passing through dispersed sample. |
| Test Item | Specification |
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| Appearance | White to off white solid |
| Purity(HPLC) | ≥99.0% |
| Refractive index at 20°C | -23.0 to -25.0° (C=4,HCl(1+1)) |
| Loss on drying | ≤0.5% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.