3'-(Trifluoromethyl)acetophenone Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 349-76-8 |
| Product name | 3'-(Trifluoromethyl)acetophenone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeElectronic GradeMaterial GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3'-(Trifluoromethyl)acetophenone
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3'-(Trifluoromethyl)acetophenone Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3'-(Trifluoromethyl)acetophenone
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of central nervous system agents, including antidepressants and antipsychotics | Prepared via Friedel–Crafts acylation, followed by reduction, condensation, and other steps to construct the target molecular scaffold |
| Pesticides | Used to synthesize herbicidal or insecticidal active ingredients containing a trifluoromethyl group | Serves as a key aromatic ketone intermediate in nucleophilic addition or cyclization reactions to introduce pharmacophoric groups |
| Liquid Crystal Materials | Used to prepare high-performance liquid crystal monomers or dielectric anisotropy modifiers | Attached to biphenyl or pyrimidine core structures via esterification or etherification to modulate liquid crystalline phase behavior |
| Organic Synthesis | General aromatic ketone building block for constructing complex fluorinated molecules | Participates in classical transformations including Wittig reactions, Grignard additions, and reductive aminations |
Manufacturing Quality Control of 3'-(Trifluoromethyl)acetophenone
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color and condition (usually a colorless to light yellow liquid or solid) under natural light or standard light source to determine whether it is clear and free from impurities or foreign matter. |
| Identification | Infrared Spectroscopy (IR) Proton Nuclear Magnetic Resonance (¹H NMR) Gas Chromatography-Mass Spectrometry (GC-MS) |
Confirm the compound structure consistent with 1,3,5-trifluoromethylbenzophenone by characteristic IR absorption peaks, proton NMR chemical shifts and coupling constants, or GC-MS retention time and mass spectral fragment ions. |
| Content Determination | High-Performance Liquid Chromatography (HPLC) Gas Chromatography (GC) |
Determine the main component using HPLC or GC with external or internal standard methods under specific chromatographic conditions, calculate its mass percentage content, usually requiring ≥98.0% or as per specification requirements. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) Gas Chromatography (GC) |
Separate and detect by gradient elution or programmed temperature conditions, potential by-products, unreacted raw materials, or degradation impurities generated during synthesis; individual impurities and total impurities must meet the limit requirements. |
| Moisture | Karl Fischer Titration | Determine moisture content quantitatively by reacting with Karl Fischer reagent through titration, controlling it within the specified limit (e.g., ≤0.5%). |
| Melting Point (if solid) | Capillary Melting Point Method | Load the sample into a capillary tube and slowly heat it in a melting point apparatus, record the initial and final melting temperature range, and compare with the standard value (literature value about 34–36 °C) to evaluate purity. |
| Residual Solvents | Gas Chromatography (Headspace or Direct Injection) | According to ICH Q3C guidelines, use GC to detect residual organic solvents (e.g., toluene, dichloromethane, etc.) potentially remaining from the production process, ensuring compliance with safety limits. |
| Heavy Metals | Thioacetamide Colorimetric Method or ICP-MS | Determine total heavy metal content according to pharmacopoeia methods, or use Inductively Coupled Plasma Mass Spectrometry (ICP-MS) to precisely measure residues of lead, arsenic, cadmium, mercury, etc., ensuring compliance with relevant regulatory requirements. |
Technical Specifications of 3'-(Trifluoromethyl)acetophenone
| Test Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow clear liquid |
| Purity | >=98.5% (GC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Refractive Index (n20/D) | 1.515–1.525 |
| Relative Density (20°C/25°C) | 1.170–1.190 g/cm³ |
| Odor | Characteristic ketonic odor |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3'-(Trifluoromethyl)acetophenone
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3'-(Trifluoromethyl)acetophenone
Safety Information of 3'-(Trifluoromethyl)acetophenone
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 3'-(Trifluoromethyl)acetophenone
Industrial 3'-(Trifluoromethyl)acetophenone Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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