D-Histidine Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 351-50-8 |
| Product name | D-Histidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent GradeFood GradeCosmetic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for D-Histidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk D-Histidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of D-Histidine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of antihistamine drugs | Produced via chemical synthesis or microbial fermentation for use in preparing related drug intermediates |
| Food additives | Nutritional fortificant | Prepared by microbial fermentation or chemical synthesis and incorporated into functional foods |
| Biobiochemistry | Biosynthetic intermediate | Used in the synthesis of amino acid-derived compounds, such as peptides and proteins, for research purposes |
| Cosmetics | Antioxidant | Incorporated into certain skincare formulations to regulate skin pH and provide nutritional benefits |
| Research | Laboratory research | Obtained through organic synthesis or natural extraction for biochemical experimentation and analysis |
Manufacturing Quality Control of D-Histidine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (D-Histidine Content) | Acid-Base Titration with HClO4 in non-aqueous medium | Quantifies primary amine group via potentiometric titration using perchloric acid in glacial acetic acid. |
| Optical Rotation | [alpha]D Measurement using Polarimeter | Measures specific rotation at 20 C and 589 nm to confirm chiral purity and D-configuration. |
| Loss on Drying | Gravimetric Analysis (105 C, 2 h) | Determines volatile matter by weight loss after drying under standardized temperature and time. |
| Residue on Ignition | Gravimetric Ashing (500-600 C) | Measures inorganic impurities as sulfate ash after high-temperature combustion. |
| Heavy Metals (as Pb) | Colorimetric Method with Thioacetamide | Forms colored metal-sulfide complexes in acidic medium; compared visually or spectrophotometrically against lead standard. |
| Chloride Impurity | Argentometric Titration (Mohr method) | Quantifies chloride ions by precipitation titration with silver nitrate using potassium chromate indicator. |
| Sulfate Impurity | Barium Sulfate Gravimetric Method | Precipitates sulfate as BaSO4 and determines mass after filtration and drying. |
| Related Substances | HPLC with UV Detection | Separates and quantifies structurally similar impurities (e.g., L-histidine, histamine, degradants) using reversed-phase chromatography. |
| Water Content | Karl Fischer Titration | Determines trace water via iodine-sulfur dioxide redox reaction in methanol-based reagent. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Measures hydrogen ion activity in 1% w/v aqueous solution using calibrated pH electrode. |
| Microbial Limits | Membrane Filtration and Plate Count | Detects and enumerates aerobic bacteria, yeast, and mold using selective agar media and incubation. |
| Iron Impurity | Atomic Absorption Spectroscopy (AAS) | Quantifies iron by measuring absorption of characteristic wavelength light (248.3 nm) from atomized sample. |
Technical Specifications of D-Histidine
| Test Item | Specification |
|---|---|
| Appearance | White to almost white powder or crystals |
| Purity | >=98.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Optical Rotation | -12.0 to -14.0 deg (c=1, 1M HCl) |
| Melting Point | 265 to 275 °C (decomposes) |
| Total Impurities | <=1.5% (HPLC) |
| Heavy Metals | <=20 ppm (as Pb) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of D-Histidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of D-Histidine
Packaging of D-Histidine
Industrial D-Histidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply