4-(Difluoromethoxy)benzenesulfonyl chloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 351003-34-4 |
| Product name | 4-(Difluoromethoxy)benzenesulfonyl chloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-(Difluoromethoxy)benzenesulfonyl chloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-(Difluoromethoxy)benzenesulfonyl chloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-(Difluoromethoxy)benzenesulfonyl chloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of 4-(difluoroethoxy)benzenesulfonamide derivatives | Manufacture of pharmaceutical intermediates |
| Pharmaceuticals | Preparation of antibiotics and antimicrobial agents | Pharmaceutical chemical synthesis |
| Pharmaceuticals | Synthesis of biologically active molecules, including antitumor and antiviral compounds | Pharmaceutical research and synthesis |
| Chemicals | Sulfonylation reactions in organic synthesis | Organic synthesis |
| Chemicals | Introduction of the difluoroethoxybenzenesulfonyl group as a modifying reagent | Fine chemical manufacturing |
Manufacturing Quality Control of 4-(Difluoromethoxy)benzenesulfonyl chloride
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, calibrated against certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and peak area normalization. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common organic solvents (e.g., dichloromethane, acetone) per ICH Q3C guidelines. |
| Moisture Content | Karl Fischer Titration | Coulometric or volumetric titration using iodine-based reagent to determine water content based on stoichiometric reaction. |
| Acid Value | Acid-Base Titration | Titration with standardized NaOH solution using phenolphthalein indicator to quantify acidic impurities including hydrolyzed sulfonic acid. |
| Chloride Ion Content | Ion Chromatography | Separation and quantification of Cl- ions using suppressed conductivity detection after anion exchange separation. |
| Heavy Metals | ICP-OES | Multi-element detection after acid digestion; quantifies Pb, Cd, Hg, As, Cr, and Ni against calibration standards. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid transition temperature using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against white background under controlled lighting per Ph. Eur. 2.2.1. |
| Sulfur Content | Elemental Analysis (Combustion Method) | High-temperature combustion followed by infrared detection of SO2 to determine total sulfur content. |
| Bulk Density | Graduated Cylinder Method | Measurement of mass per unit volume for free-flowing powder using standardized tapping procedure per ASTM D1895. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion using laser scattering to determine D10, D50, D90 values per ISO 13320. |
Technical Specifications of 4-(Difluoromethoxy)benzenesulfonyl chloride
| Test Item | Specification |
|---|---|
| Appearance | Light yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Odor | Characteristic pungent odor |
| Color (APHA/Pt-Co) | <=100 |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-(Difluoromethoxy)benzenesulfonyl chloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-(Difluoromethoxy)benzenesulfonyl chloride
Safety Information of 4-(Difluoromethoxy)benzenesulfonyl chloride
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 4-(Difluoromethoxy)benzenesulfonyl chloride
Industrial 4-(Difluoromethoxy)benzenesulfonyl chloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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