China Factory Direct
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| CAS number | 351003-43-5 |
| Product name | 3,4,5-TRIFLUOROBENZENESULFONYL CHLORIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of fluorinated pharmaceutical intermediates | Used as a sulfonyl chloride reagent to form sulfonamide bonds with amines, enabling construction of molecular scaffolds for antiviral, anticancer, or central nervous system drugs |
| Agrochemicals | Synthesis of fluorinated fungicides/insecticides | Condensed with heterocyclic amines or aromatic amines to prepare fluorinated sulfonamide agrochemicals with high biological activity |
| Materials Science | Synthesis of high-performance polymer monomers | Applied as a fluorinated sulfonyl chloride monomer in copolymerization reactions to produce heat- and chemical-resistant fluorinated polymers |
| Organic Synthesis | General sulfonylation reagent | Reacts with alcohols, amines, or thiols under basic conditions to introduce the trifluorobenzenesulfonyl group, facilitating protecting-group strategies or molecular functionalization |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detector | Quantitative determination based on peak area comparison against certified reference standard under optimized chromatographic conditions. |
| Related Substances | High Performance Liquid Chromatography (HPLC) with UV detection | Separation and quantification of impurities using reverse-phase C18 column and gradient elution with UV absorbance detection. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) with FID | Volatile organic solvents are extracted into headspace and quantified by GC-FID using calibrated standards. |
| Moisture Content | Karl Fischer Titration (Coulometric mode) | Electrochemical titration where iodine generated coulometrically reacts stoichiometrically with water in the sample. |
| Acid Value | Acid-Base Titration with NaOH standard solution | Neutralization of acidic impurities (e.g., sulfonic acid) using standardized sodium hydroxide solution and potentiometric endpoint detection. |
| Chloride Ion Impurity | Ion Chromatography (IC) with conductivity detection | Separation of anions on ion-exchange column followed by quantitative detection of chloride via suppressed conductivity. |
| Heavy Metals (Pb, Cd, Hg, As) | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Multi-element trace metal quantification after acid digestion and dilution, using isotopic mass detection. |
| Sulfur Content | Combustion IC (Oxidative combustion followed by IC) | Organic sulfur converted to sulfate upon high-temperature combustion, then quantified by ion chromatography. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed as solid-to-liquid phase change using calibrated capillary method per USP <741>. |
| Appearance | Visual Inspection against Standard White Background | Assessment of physical state, color, and presence of particulates or discoloration under controlled lighting. |
| Residue on Ignition | Gravimetric Analysis after High-Temperature Ashing | Non-volatile inorganic residue determined by weight difference before and after ignition at 700-800 C. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light induced by chiral impurities or degradation products in solution. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Melting Point | 35–39°C |
| Refractive Index (n20/D) | 1.495–1.505 |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.