China Factory Direct
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| CAS number | 3512-17-2 |
| Product name | 2,4,6-TRIFLUOROPYRIDINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Synthesis of pharmaceutical intermediates | Fluorination and coupling reactions |
| Agrochemical Industry | Preparation of fluorinated agrochemical intermediates | Fluorination and cyclization reactions |
| Materials Chemistry | Functional polymer monomers | Polymerization |
| Organic Synthesis | Synthesis of specialty chemicals | Nucleophilic substitution, cross-coupling, and related reactions |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Purity (Active Ingredient Content) | High-Performance Liquid Chromatography (HPLC) | A C18 reverse-phase chromatographic column is used with methanol-water or acetonitrile-water as the mobile phase. The UV detector (220–254 nm) measures the main peak area, and content is calculated using external standard or internal standard methods, effectively separating impurities. |
| Impurity Profile (Organic Impurities) | HPLC-UV / HPLC-MS | After HPLC separation, mass spectrometry (MS) is used for detection to identify and quantify known/unknown impurities (e.g., mono-fluoro/di-fluoro pyridine derivatives, unreacted raw materials, by-products), suitable for trace impurity control. |
| Moisture Content | Karl Fischer Titration | Iodine-sulfur dioxide-pyridine-methanol system quantitatively reacts with water; electrochemical or endpoint indication is used to determine moisture content, suitable for accurate determination of trace water (<1000 ppm). |
| Volatile Organic Impurities | Gas Chromatography (GC) | A capillary column (e.g., DB-5 or HP-INNOWAX) with FID detector is used, employing headspace or direct injection to detect residual solvents (e.g., methanol, acetonitrile, DMF) and low-boiling-point fluorinated byproducts. |
| Fluorine Content | Ionic Chromatography (IC) or Fluoride Ion-Selective Electrode | The sample is hydrolyzed under alkaline conditions or combusted in an oxygen bomb to release fluoride ions, which are then detected by ion chromatography or a fluoride ion-selective electrode to verify the integrity of the three fluorine atoms in the molecule. |
| Melting Point | Melting Point Apparatus | A digital melting point apparatus is used to determine the melting range (literature value approximately 15–17 °C), for preliminary identification and batch consistency assessment. |
| Appearance and Color | Visual Inspection / Colorimetry | The sample is observed to be a colorless to slightly yellow transparent liquid. A colorimeter (e.g., APHA or Pt-Co standard) is used to quantify color, controlling product visual quality. |
| pH Value (Aqueous Solution) | pH Meter Measurement | The sample is dissolved in an appropriate amount of water (note hydrolyzability), and a calibrated pH meter is used to measure the solution pH, evaluating its acidity/alkalinity (typically neutral to slightly acidic). |
| Heavy Metal Residues | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample digestion, AAS or ICP-MS is used to determine heavy metal content such as lead, cadmium, mercury, and arsenic, meeting ICH Q3D or pharmacopoeia limits (e.g., ≤10 ppm). |
| Content Uniformity (Between Batches) | Multi-batch Replicate HPLC Determination | The active ingredient is quantified by HPLC across multiple batches, and RSD (relative standard deviation) is calculated to ensure process stability and batch-to-batch consistency (typically required RSD ≤2.0%). |
| Test Item | Specification |
|---|---|
| Appearance | Colorless liquid |
| Purity | >=98.5% (GC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Refractive Index (n20/D) | 1.405–1.415 |
| Relative Density (20°C/25°C) | 1.220–1.240 g/cm³ |
| Identification (NMR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.