1-BROMO-CYCLOBUTANECARBOXYLIC ACID ETHYL ESTER Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 35120-18-4 |
| Product name | 1-BROMO-CYCLOBUTANECARBOXYLIC ACID ETHYL ESTER |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1-BROMO-CYCLOBUTANECARBOXYLIC ACID ETHYL ESTER
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-BROMO-CYCLOBUTANECARBOXYLIC ACID ETHYL ESTER Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-BROMO-CYCLOBUTANECARBOXYLIC ACID ETHYL ESTER
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Used in synthesizing active pharmaceutical ingredients (APIs) containing a cyclobutyl moiety, such as antiviral agents and kinase inhibitors | Serves as a cyclobutyl building block, introduced into target molecules via palladium-catalyzed cross-coupling or nucleophilic substitution |
Manufacturing Quality Control of 1-BROMO-CYCLOBUTANECARBOXYLIC ACID ETHYL ESTER
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detector | Quantifies main component by retention time and peak area against certified reference standard. |
| Related Substances | Gas Chromatography-Mass Spectrometry (GC-MS) | Identifies and semi-quantifies impurities based on mass spectral fragmentation patterns and retention behavior. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Measures volatile organic solvents (e.g., toluene, ethyl acetate) using equilibrium vapor phase analysis. |
| Water Content | Karl Fischer Titration (Coulometric mode) | Determines water via electrochemical iodine generation and stoichiometric reaction with water. |
| Acid Value | Acid-Base Titration with NaOH standard solution | Measures free carboxylic acid groups by neutralization with standardized sodium hydroxide. |
| Halogen Content (Br) | Oxygen Flask Combustion followed by Potentiometric Titration | Converts organic bromine to bromide ion; quantified by silver nitrate titration with potentiometric endpoint detection. |
| Heavy Metals (Pb, Cd, Hg, As) | Inductively Coupled Plasma-Optical Emission Spectrometry (ICP-OES) | Digests sample and measures trace metal concentrations via element-specific atomic emission intensities. |
| Appearance | Visual Inspection against Standard White Background | Assesses physical state, color, and clarity under controlled lighting and viewing conditions. |
| Density | Digital Density Meter (Oscillating U-tube principle) | Determines mass per unit volume from resonant frequency shift of a vibrating U-shaped tube filled with sample. |
| Refractive Index | Refractometry (Abbe refractometer) | Measures ratio of light velocity in air vs. sample at specified temperature using critical angle of total internal reflection. |
| Boiling Point | Capillary Boiling Point Apparatus (Siwoloboff method) | Determines temperature at which vapor pressure equals atmospheric pressure using capillary tube immersion technique. |
| Chloride Impurity | Ion Chromatography (IC) with Conductivity Detection | Separates and quantifies chloride ions after sample dissolution and filtration, using anion-exchange column and conductivity measurement. |
Technical Specifications of 1-BROMO-CYCLOBUTANECARBOXYLIC ACID ETHYL ESTER
| Test Item | Specification |
|---|---|
| Appearance | Colorless liquid |
| Purity | >=98.0% (GC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Refractive Index (n20/D) | 1.475–1.485 |
| Relative Density (20°C/25°C) | 1.32–1.34 g/cm³ |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1-BROMO-CYCLOBUTANECARBOXYLIC ACID ETHYL ESTER
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1-BROMO-CYCLOBUTANECARBOXYLIC ACID ETHYL ESTER
Safety Information of 1-BROMO-CYCLOBUTANECARBOXYLIC ACID ETHYL ESTER
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 1-BROMO-CYCLOBUTANECARBOXYLIC ACID ETHYL ESTER
Industrial 1-BROMO-CYCLOBUTANECARBOXYLIC ACID ETHYL ESTER Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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