4,6-Dimethyl-2-methylsulfonylpyrimidine Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 35144-22-0 |
| Product name | 4,6-Dimethyl-2-methylsulfonylpyrimidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for 4,6-Dimethyl-2-methylsulfonylpyrimidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4,6-Dimethyl-2-methylsulfonylpyrimidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4,6-Dimethyl-2-methylsulfonylpyrimidine
| Industry | Application | Process |
|---|---|---|
| Pesticides | Herbicide intermediate for synthesizing sulfonylurea herbicides (e.g., bensulfuron-methyl, pyrazosulfuron-ethyl) | Serves as a key pyrimidine ring substituent; couples with aniline derivatives in condensation reactions to construct the sulfonylurea bridge |
| Pharmaceuticals | Potential kinase inhibitor scaffold in anticancer drug research | Used to build pyrimidine-sulfonamide compound libraries for screening inhibitory activity against targets such as CDK and VEGFR |
Manufacturing Quality Control of 4,6-Dimethyl-2-methylsulfonylpyrimidine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC with UV detection; identification based on retention time matching and threshold limits per ICH Q3B. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., methanol, acetone, ethyl acetate) against calibration standards. |
| Water Content | Karl Fischer Titration | Volumetric titration using iodine, sulfur dioxide, and pyridine in methanol to determine water content based on stoichiometric reaction. |
| Heavy Metals | ICP-MS | Quantitative determination of elemental impurities (e.g., Pb, Cd, As, Hg) after acid digestion, using inductively coupled plasma mass spectrometry for sub-ppb sensitivity. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride ions in aqueous extract; quantified against sodium chloride calibration curve. |
| Sulfate Impurity | Ion Chromatography | Anion exchange chromatography with suppressed conductivity detection for sulfate quantification in sample solution. |
| Residue on Ignition | Gravimetric Analysis | Weighing residue remaining after incineration at 700-800 C to assess inorganic ash content. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range over which solid transitions to liquid, indicating purity and identity via comparison to reference standard. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passed through solution to confirm chiral integrity and absence of racemization. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion using laser scattering to determine D10, D50, D90 values per USP <429>. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic microorganisms and detection of specified pathogens (e.g., E. coli, S. aureus) following compendial culture-based methods. |
Technical Specifications of 4,6-Dimethyl-2-methylsulfonylpyrimidine
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 128–132°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of 4,6-Dimethyl-2-methylsulfonylpyrimidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4,6-Dimethyl-2-methylsulfonylpyrimidine
Safety Information of 4,6-Dimethyl-2-methylsulfonylpyrimidine
| Pictograms |   |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 4,6-Dimethyl-2-methylsulfonylpyrimidine
Industrial 4,6-Dimethyl-2-methylsulfonylpyrimidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply