D-1-N-Boc-prolinamide Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 35150-07-3 |
| Product name | D-1-N-Boc-prolinamide |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for D-1-N-Boc-prolinamide
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk D-1-N-Boc-prolinamide Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of D-1-N-Boc-prolinamide
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of peptides and proteins | Used to protect the amino group of amino acids, followed by deprotection |
| Medical | Development of therapeutic peptide drugs | Introduced via solid-phase or liquid-phase peptide synthesis |
| Biotechnology | Research tool compound | Used in stepwise peptide sequence synthesis |
| Chemical | Preparation of other organic compounds | Introduced as a functional group into starting materials to participate in substitution or condensation reactions |
Manufacturing Quality Control of D-1-N-Boc-prolinamide
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 200–220 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV/MS | Detects and semi-quantifies impurities (e.g., residual Boc-L-proline, deprotection by-products) via gradient HPLC coupled with UV and/or mass spectrometric detection. |
| Residual Solvents | GC-FID | Measures trace organic solvents (e.g., THF, DMF, ethyl acetate) using gas chromatography with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration (Coulometric) | Determines water content electrochemically by iodine generation and stoichiometric reaction with water in anhydrous methanol-based reagent. |
| Heavy Metals | ICP-MS | Quantifies trace metals (e.g., Pd, Ni, Fe, Cu) after acid digestion using inductively coupled plasma mass spectrometry with isotope-dilution calibration. |
| Optical Rotation | [α]D | Measures specific optical rotation at 589 nm (Na-D line) in specified solvent/concentration to confirm chiral integrity and enantiomeric purity. |
| Residual Chloride | Ion Chromatography (IC) | Quantifies chloride ions from hydrochloride salt residues or synthesis intermediates using suppressed conductivity detection. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary apparatus per USP <741>. |
| Particle Size Distribution | Laser Diffraction | Measures particle size distribution in dry or dispersed state using Mie scattering theory and laser diffraction principles. |
| Microbial Contamination | Membrane Filtration + TSA/TSA+SCDA | Detects aerobic microorganisms per Ph. Eur. 2.6.12 using membrane filtration followed by incubation on tryptic soy agar or soy-casein digest agar. |
| pH (Aqueous Suspension) | pH Meter | Measures pH of a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode to assess acidic/basic impurity burden. |
| Residual Palladium | ICP-OES | Quantifies palladium catalyst residue after microwave-assisted acid digestion using inductively coupled plasma optical emission spectroscopy. |
| Chiral Purity | Chiral HPLC | Evaluates enantiomeric excess using chiral stationary phase HPLC with UV detection, comparing retention times and peak areas to L- and D-enantiomer standards. |
| Loss on Drying (LOD) | Thermogravimetric Analysis (TGA) | Determines volatile content by measuring mass loss upon controlled heating (e.g., 105 °C, 2 h) under nitrogen or air per USP <731>. |
Technical Specifications of D-1-N-Boc-prolinamide
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | -47.0 to -43.0 deg (c=1, in methanol) |
| Melting Point | 128 to 132 °C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of D-1-N-Boc-prolinamide
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of D-1-N-Boc-prolinamide
Packaging of D-1-N-Boc-prolinamide
Industrial D-1-N-Boc-prolinamide Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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