China Factory Direct
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| CAS number | 35193-64-7 |
| Product name | (S)-(+)-1,1'-Binaphthyl-2,2'-diyl hydrogenphosphate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Chiral catalyst precursor | Used to synthesize chiral ligands for asymmetric catalysis and employed in transition metal-catalyzed coupling reactions |
| Organic synthesis | Asymmetric synthesis reagent | Serves as a key intermediate for constructing chiral centers, applied in the synthesis of natural products and active pharmaceutical ingredients (APIs) |
| Materials science | Functional molecular design | Used to prepare polymers or functional materials with defined stereochemistry, enhancing chiral recognition performance |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Chemical Purity | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column with gradient elution of methanol-water or acetonitrile-water. Detection is performed using a UV detector (254 nm) to quantify the main component and evaluate impurity peak areas for purity calculation. Suitable for separating chiral isomers and degradation products. |
| Chiral Purity (Enantiomeric Excess, ee Value) | Chiral High-Performance Liquid Chromatography (Chiral HPLC) | Employs chiral stationary phase columns (e.g., Chiralpak AD-H, OD-H, or Chiralcel OB-H) with n-hexane-isopropanol as the mobile phase. The ratio of S- and R-enantiomers is quantified by comparing retention times with reference standards to calculate the ee value. |
| Water Content | Karl Fischer Titration | Uses a reagent composed of iodine, sulfur dioxide, pyridine, and methanol that reacts quantitatively with water. The endpoint is determined potentiometrically or amperometrically to accurately measure trace moisture levels, compliant with pharmacopeial requirements (e.g., USP/EP). |
| Melting Point | Melting Point Apparatus | Determines the melting range using capillary method or automated melting point instrument. Comparison with literature values or reference standards helps assess crystal purity and consistency of crystalline form. |
| UV Absorption Characteristics | Ultraviolet-Visible Spectrophotometry (UV-Vis) | Scans absorption spectrum in the 200–400 nm wavelength range to identify maximum absorption wavelength (λmax), used for qualitative identification and quantitative analysis (in conjunction with HPLC). |
| Infrared Functional Group Identification | Fourier Transform Infrared Spectroscopy (FT-IR) | Obtains infrared spectra via KBr pellet or ATR technique to identify characteristic absorption peaks such as P=O, P–O–C, aromatic C=C, etc., confirming molecular structure integrity and detecting impurity functional groups. |
| Heavy Metal Residues | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After acid digestion of the sample, AAS or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) is used to determine residual levels of heavy metals such as Pb, Cd, Hg, As, Cu, meeting ICH Q3D or pharmacopeial limits. |
| Residual Solvents | Gas Chromatography (GC) | Uses headspace or direct injection with a capillary column (e.g., DB-624) and FID detector to detect residual organic solvents such as ethanol, acetone, dichloromethane, and acetonitrile, complying with ICH Q3C guidelines. |
| Thermal Stability / Decomposition Temperature | Thermogravimetric Analysis (TGA) | Heats the sample under nitrogen or air atmosphere at a programmed rate, monitoring mass change versus temperature to assess onset of thermal decomposition and weight loss behavior, useful for evaluating material stability and setting storage conditions. |
| Crystal Form Identification | X-Ray Powder Diffraction (XRPD) | Measures the diffraction pattern of the sample and compares it with standard patterns to confirm the presence of polymorphism and ensure physical property consistency across batches. |
| Chloride Ions / Inorganic Anions | Ion Chromatography (IC) | Uses an anion-exchange column with conductivity detection to measure inorganic impurities such as Cl⁻, SO₄²⁻ that may be introduced during manufacturing, applicable for controlling inorganic salt residues in active pharmaceutical ingredients. |
| Test Item | Specification |
|---|---|
| Appearance | White Solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | +605° to +615° (c=1, CHCl3) |
| Melting Point | 178°C to 182°C |
| Identification (NMR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.