China Factory Direct
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| CAS number | 35264-09-6 |
| Product name | 1-N-Boc-Aminocyclopentanecarboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | As an amino acid derivative, used as a protecting group in peptide synthesis | Applied in solid-phase or solution-phase peptide synthesis, where Boc-1-aminocyclopentanecarboxylic acid serves as a chiral building block: the N-terminal amino group is protected with Boc, and the carboxyl group participates in coupling reactions to form non-natural amino acid residues |
| Pharmaceuticals | For synthesizing biologically active cyclic amino acid derivatives | After Boc deprotection, coupled with other amino acids or functional groups to construct drug molecules containing a cyclopentane scaffold, such as protease inhibitors or neurotransmitter analogs |
| Chemical Research | As an organic synthesis intermediate for constructing complex heterocyclic compounds | In laboratory-scale synthesis, subjected to Boc deprotection, cyclization, or condensation reactions to prepare nitrogen-containing heterocycles or peptidomimetic compounds, supporting drug discovery research |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~200–210 nm, comparing peak area against a certified reference standard. |
| Chiral Purity | Chiral HPLC | Enantiomeric excess assessment via separation on a chiral stationary phase (e.g., Chiralpak AD-H), with UV detection and comparison to enantiopure reference. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents (e.g., ethyl acetate, toluene, methanol) using gas chromatography with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration based on the stoichiometric reaction of iodine with water in a pyridine/methanol solvent system. |
| Heavy Metals (as Pb) | ICP-MS | Multi-element trace metal quantification after acid digestion, using inductively coupled plasma mass spectrometry for sub-ppb sensitivity. |
| Residual Palladium | ICP-OES | Quantification of palladium catalyst residues post-hydrogenation, via acid digestion followed by inductively coupled plasma optical emission spectroscopy. |
| Acid Value | Acid-Base Titration | Neutralization of carboxylic acid groups with standardized NaOH solution using phenolphthalein or potentiometric endpoint detection. |
| Optical Rotation | [α]D Measurement | Specific rotation determination at 589 nm (Na D-line) using a polarimeter, reporting degrees per dm·g/mL in specified solvent (e.g., 1 M HCl). |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample using Mie scattering theory to determine volume-based particle size distribution (D10, D50, D90). |
| Microbial Contamination | Bioburden Testing (USP <61>) | Membrane filtration followed by aerobic plate count on Tryptic Soy Agar, incubated at 30–35 °C for 3–5 days. |
| Related Substances | HPLC-UV (Forced Degradation) | Detection and quantification of structurally related impurities (e.g., Boc-deprotected amine, dimer, hydrolysis products) under stressed conditions (acid, base, heat, oxidation). |
| Test Item | Specification |
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| Appearance | Yellow solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 145-149°C |
| Optical Rotation | -15.0 to -19.0° (c=1, in 1N HCl) |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.