6-Chloro-5-nitropyridine-2-carboxylic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 353277-27-7 |
| Product name | 6-Chloro-5-nitropyridine-2-carboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 6-Chloro-5-nitropyridine-2-carboxylic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 6-Chloro-5-nitropyridine-2-carboxylic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 6-Chloro-5-nitropyridine-2-carboxylic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of antiviral agents (e.g., HCV NS5A inhibitors) | Further elaborated into active pharmaceutical ingredients via nucleophilic substitution, reduction, or coupling reactions |
| Agrochemicals | Intermediate for synthesizing novel pyridine-based insecticides or herbicides | Converted into target agrochemical compounds through organic synthesis steps including amidation, halogen exchange, or ring modification |
| Chemical Research | Multifunctional synthon for constructing nitrogen-containing heterocycles | Selectively transformed via its chloro and nitro functional groups for structure–activity relationship studies in medicinal chemistry or materials science |
Manufacturing Quality Control of 6-Chloro-5-nitropyridine-2-carboxylic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., isomers, dechlorinated or denitrated analogs) via gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, dichloromethane, DMF) using gas chromatography with flame ionization detection. |
| Heavy Metals | ICP-MS | Determines trace metal contaminants (e.g., Pb, Cd, Ni, Cu) by inductively coupled plasma mass spectrometry after acid digestion. |
| Chloride Content | Ion Chromatography | Quantifies chloride ion impurity using suppressed ion chromatography with conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Measures inorganic residue after high-temperature incineration of sample with sulfuric acid pretreatment. |
| Moisture Content | Karl Fischer Titration | Determines water content by coulometric or volumetric titration using iodine-based redox reaction in anhydrous methanol. |
| Melting Point | Capillary Melting Point Apparatus | Measures temperature range at which solid transitions to liquid, indicating crystallinity and presence of impurities. |
| Particle Size Distribution | Laser Diffraction | Analyzes particle size distribution in dry or wet dispersion using Mie scattering theory. |
| pH of Aqueous Suspension | pH Meter | Measures pH of a standardized suspension (e.g., 1% w/v in water) to assess acidic impurities or degradation products. |
| Organic Volatile Impurities (OVI) | GC-MS | Identifies and quantifies unspecified volatile organic impurities using gas chromatography coupled with mass spectrometry. |
| Appearance | Visual Inspection | Assesses physical form, color, and homogeneity against a defined standard (e.g., off-white to light yellow crystalline powder). |
Technical Specifications of 6-Chloro-5-nitropyridine-2-carboxylic acid
| Test Item | Specification |
|---|---|
| Appearance | Light-green solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 182–186°C |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 6-Chloro-5-nitropyridine-2-carboxylic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 6-Chloro-5-nitropyridine-2-carboxylic acid
Safety Information of 6-Chloro-5-nitropyridine-2-carboxylic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 6-Chloro-5-nitropyridine-2-carboxylic acid
Industrial 6-Chloro-5-nitropyridine-2-carboxylic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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