tert-butyl 5-oxo-L-prolinate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 35418-16-7 |
| Product name | tert-butyl 5-oxo-L-prolinate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeMaterial GradeSpecialty GradeReagent GradeIndustrial GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for tert-butyl 5-oxo-L-prolinate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk tert-butyl 5-oxo-L-prolinate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of tert-butyl 5-oxo-L-prolinate
| Industry | Application | Process Description |
|---|---|---|
| Pharmaceutical R&D | Drug synthesis intermediate | Used in the synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs) as a chiral building block |
| Chemical synthesis | Chiral reagent | Applied as a chiral auxiliary or catalyst in asymmetric synthesis to control stereoselectivity |
| Biochemistry | Peptide synthesis | Applied as a protected amino acid derivative for introducing the pyroglutamic acid moiety in solid-phase or solution-phase peptide synthesis |
| Pharmaceutical manufacturing | Anticancer drug intermediate | Used as a key intermediate in the synthetic route of certain antitumor agents |
| Analytical chemistry | Reference standard | Applied as a reference material in analytical techniques such as high-performance liquid chromatography (HPLC) for detection and quantitative analysis |
| Materials science | Functional material synthesis | Applied as a structural unit or crosslinking agent in the synthesis of specialty functional materials or polymers |
| Agrochemical R&D | Agrochemical active ingredient synthesis | Used as an organic synthesis intermediate in constructing agrochemical molecules to enhance biological activity or stability |
| Food chemistry | Food additive research | Applied as a structural analog or reaction intermediate in the study of flavor compounds or food preservatives |
| Organocatalysis | Catalyst design | Used in designing novel organocatalysts to facilitate organic reaction activation and transition-state modulation |
| Environmental chemistry | Pollutant degradation studies | Applied as a model compound or auxiliary reagent in environmentally benign degradation reactions |
Manufacturing Quality Control of tert-butyl 5-oxo-L-prolinate
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 210 nm, calibrated against certified reference standard. |
| Related Substances | HPLC-UV | Separation and detection of impurities using gradient HPLC-UV; identification based on retention time relative to reference standards. |
| Residual Solvents | GC-FID | Detection and quantification of common solvents (e.g., MTBE, hexane, ethyl acetate) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Coulometric or volumetric titration using iodine generation to quantify water based on stoichiometric reaction with Karl Fischer reagent. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to confirm chiral integrity and enantiomeric purity. |
| Heavy Metals | ICP-OES | Simultaneous multi-element detection after acid digestion; quantification against calibration standards per USP <232>. |
| Residual Palladium | ICP-MS | Ultra-trace quantification of Pd after microwave-assisted digestion, using isotope dilution for highest accuracy. |
| Chloride Content | Ion Chromatography | Separation and conductivity detection of chloride ions in aqueous extract; quantified against NaCl calibration curve. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, indicating crystallinity and absence of significant impurities. |
| Loss on Drying | Gravimetric Analysis | Weight loss measured after drying under controlled temperature and vacuum, reflecting volatile and moisture content. |
| pH of Aqueous Solution | Potentiometric pH Measurement | pH measurement of saturated aqueous suspension using calibrated glass electrode per USP <791>. |
| Particle Size Distribution | Laser Diffraction | Size analysis of dry powder dispersion via light scattering pattern analysis, reporting D10, D50, D90 values. |
Technical Specifications of tert-butyl 5-oxo-L-prolinate
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (GC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | +8.0 to +10.0 deg (c=1, in CHCl3) |
| Melting Point | 68 to 72 °C |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of tert-butyl 5-oxo-L-prolinate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of tert-butyl 5-oxo-L-prolinate
Packaging of tert-butyl 5-oxo-L-prolinate
Industrial tert-butyl 5-oxo-L-prolinate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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