China Factory Direct
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| CAS number | 35450-37-4 |
| Product name | METHYL 3-BROMO-4-METHOXYBENZOATE 98 |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate for the synthesis of the antiplatelet drug ticagrelor | Undergoes Suzuki or Buchwald–Hartwig coupling with amines under palladium catalysis to construct the pyrimido-fused ring system |
| Pesticide R&D | Structural modification unit for novel insecticidal or fungicidal molecules | Converted through multi-step transformations—including hydrolysis, reduction, and halogen exchange—to introduce bioactive heterocyclic groups |
| Organic Synthesis | Functionalized building block for constructing bromo-methoxybenzoate scaffolds | Participates in reactions such as lithium–bromine exchange followed by addition to electrophiles (e.g., aldehydes, CO₂), or transition metal-catalyzed processes including Heck coupling and Ullmann condensation |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample under natural light or standard illumination to assess color and physical state (typically white to off-white crystalline powder) for compliance with specifications. |
| Identification | Infrared Spectroscopy (IR) High-Performance Liquid Chromatography (HPLC) Proton Nuclear Magnetic Resonance (¹H NMR) |
Identification is performed by comparing characteristic absorption peaks in the IR spectrum with a reference spectrum; or by matching the HPLC retention time with that of a reference standard; alternatively, structural features can be confirmed via chemical shifts and coupling constants in ¹H NMR. |
| Assay | High-Performance Liquid Chromatography (HPLC) | A reverse-phase C18 column is used with a mobile phase of methanol-water or acetonitrile-water, and detection is performed using a UV detector (typically at ~254 nm). The content of the main component is calculated by the external standard method, with a typical requirement of ≥98.0%. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Gradient or isocratic elution conditions are employed to separate and detect potential impurities (e.g., starting materials, intermediates, by-products, and degradation products). Single and total impurity limits are controlled using area normalization or self-reference methods. |
| Residual Solvents | Gas Chromatography (GC) | Following ICH Q3C guidelines, residual organic solvents (e.g., methanol, dichloromethane, toluene) are detected and quantified using headspace or direct injection GC-FID; the quantification limit must meet specified thresholds. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Atmospheric Constant-Temperature Drying | The sample is dried at 105°C to constant weight, and the percentage of mass loss is measured to control moisture and volatile substances, typically requiring ≤0.5%. |
| Melting Point | Capillary Melting Point Determination | The melting range (from initial to final melting) is measured using a melting point apparatus and compared with the literature value (approximately 85–88°C) to assess purity and consistency. |
| pH Value (if applicable) | pH Meter Method | If formulated as an aqueous solution (e.g., 1%), the pH is measured using a calibrated pH meter to evaluate the presence of free acidic or basic impurities. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 72–76°C |
| Identification (NMR) | Conforms to reference standard |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.