China Factory Direct
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| CAS number | 35453-19-1 |
| Product name | 5-Amino-2,4,6-triiodoisophthalic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Key intermediate for non-ionic X-ray contrast agents | Synthesis of non-ionic contrast agents (e.g., iohexol, iodixanol, ioversol) via acid chloride formation, esterification, and amination |
| Pharmaceutical Industry | Intermediate for ionic contrast agents | Structural modification of ionic contrast agent derivatives (e.g., diatrizoic acid) |
| Diagnostic Reagents | Raw material for medical imaging contrast agents | Serves as a high-iodine-content core scaffold (iodine content ~76%) to incorporate drug molecules and enhance X-ray imaging contrast |
| Chemical Synthesis | Organic synthesis building block | Derivatization (e.g., amidation, esterification) using the molecule’s amino and carboxyl groups to construct polyiodinated aromatic compounds |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Chemical Structure Confirmation | Infrared Spectroscopy (IR) | Verify functional groups such as amino, carboxyl, and aromatic ring iodine substituents based on characteristic absorption peaks. |
| Proton Nuclear Magnetic Resonance (¹H NMR) | Analyze chemical shifts and coupling constants of hydrogen atoms to confirm molecular framework and substitution positions. | |
| Mass Spectrometry (MS) | Determine molecular ion peaks (e.g., [M-H]⁻) and fragment ions to confirm molecular weight and fragmentation behavior. | |
| Purity Analysis | High-Performance Liquid Chromatography (HPLC) | Use reversed-phase C18 column with UV detector (~254 nm) to quantify the main component and separate impurities, then calculate purity percentage. |
| Thin-Layer Chromatography (TLC) | Rapid screening of impurities using silica gel plates and appropriate developing systems; observe number of spots and Rf values after visualization. | |
| Assay | HPLC with External Standard or Internal Standard Method | Precisely determine the concentration of the target compound in the sample by comparing peak areas with those of known standard solutions. |
| Iodine Content Determination | Redox Titration (Iodometry) | Release iodine via reduction reaction, followed by titration with sodium thiosulfate to calculate total iodine content for assessing substitution completeness. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Oven Drying Method | Determine percentage weight loss of volatile components or moisture under specified temperature (e.g., 105°C) to constant weight. |
| Residual Solvents | Gas Chromatography (GC-FID/HS-GC) | Headspace or direct injection to detect residual organic solvents (e.g., DMF, ethanol) from the synthesis process. |
| Heavy Metal Residues | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Detect trace metal elements (e.g., Pb, As, Hg) to ensure compliance with pharmacopoeial or ICH Q3D limits. |
| pH Value and Solubility | pH Meter Method / Solubility Test | Measure pH of aqueous solution; observe dissolution behavior in specified solvents (e.g., water, ethanol) to evaluate suitability for formulation. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 245-249°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.