2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 35480-52-5 |
| Product name | 2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of antitumor agents | Used as an intermediate in synthetic reactions, including esterification and amidation, to construct the target molecular structure. |
| Agrochemicals | Herbicide production | Applied in the preparation of certain herbicide precursors, primarily via transesterification and related reaction pathways. |
| Materials Science | Preparation of specialty-performance polymers | Employed as a monomer or modifier in polymer synthesis to enhance thermal stability or other material properties. |
| Fine Chemicals | Development of novel functional chemicals | Utilized as a fundamental raw material for synthesizing various functional compounds, such as surfactants and fluorescent whitening agents. |
Manufacturing Quality Control of 2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection / Observation Method | Observe the color, physical state, and presence of visible impurities under natural or standard lighting. Typically appears as white to off-white powder. |
| Assay (Content Determination) | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column with acetonitrile/water or buffer-containing mobile phases (e.g., phosphate buffers) under isocratic or gradient elution. The analyte is quantified using a UV detector (commonly set at 220–254 nm). Purity is calculated via external or internal standard method. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Same as above; optimized chromatographic conditions are used to separate and detect potential impurities such as synthesis intermediates, by-products, or degradation products. Individual impurity levels are assessed using peak area normalization or reference standard (external standard) methods. |
| Residual Solvents | Gas Chromatography (GC) | Analyzes residual organic solvents (e.g., dichloromethane, ethanol, ethyl acetate) based on manufacturing processes, using headspace or direct solution injection with FID detection. Complies with ICH Q3C guidelines. |
| Water Content (Moisture) | Karl Fischer Titration | Determines water content precisely using an automatic moisture analyzer, either by coulometric or volumetric method. Suitable for compounds sensitive to moisture. |
| Melting Point | Melting Point Determination (Capillary Method or DSC) | The melting temperature range is measured using a melting point apparatus; Differential Scanning Calorimetry (DSC) provides more accurate determination of melting point and crystalline characteristics. |
| Infrared Spectrum (IR) | Fourier Transform Infrared Spectroscopy (FT-IR) | Infrared absorption spectrum is obtained by pressing the sample with KBr or using an ATR accessory. The resulting spectrum is compared with a reference spectrum to confirm structural consistency of functional groups. |
| Nuclear Magnetic Resonance (NMR) | ¹H-NMR and ¹⁹F-NMR | Dissolve sample in deuterated solvent (e.g., DMSO-d6); molecular structure is verified using proton and fluorine NMR, particularly confirming substitution patterns of trifluoroethoxy and phenyl groups. |
| Mass Consistency | Liquid Chromatography-Mass Spectrometry (LC-MS) | Used to confirm molecular ion peaks ([M-H]⁻ or [M+X]⁺), aiding in structural confirmation and identification of impurity structures. |
| Particle Size Distribution | Laser Diffraction Particle Size Analysis | Measures particle size distribution for active pharmaceutical ingredients intended for formulation, influencing solubility and bioavailability. |
| Residue on Ignition / Sulfated Ash | Gravimetric Method | The sample is ignited at high temperature and the residue is weighed to evaluate inorganic impurity content. |
| Heavy Metals | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Atomic Absorption Spectroscopy (AAS) | Determines residual toxic elements such as lead, cadmium, mercury, and arsenic, in compliance with pharmacopoeial standards or ICH Q3D elemental impurity limits. |
Technical Specifications of 2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid
| Test Item | Specification |
|---|---|
| Appearance | White to almost white crystalline powder |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 142–146°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Acid Value (mg KOH/g) | 220–230 mg KOH/g |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid
Safety Information of 2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid
Industrial 2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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