China Factory Direct
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| CAS number | 3556-60-3 |
| Product name | 3-METHOXY-4-METHYLBENZONITRILE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | Key intermediate for synthesizing pyrethroid insecticides (e.g., lambda-cyhalothrin) | Introduces the benzylic side chain structure in target pyrethroids via diazotization–cyanation or halogenation–cyanation |
| Pharmaceuticals | Aromatic nitrile building block for antitumor agents (e.g., BTK inhibitors) and anti-inflammatory drugs | Serves as an aryl substituent in Suzuki coupling, reductive amination, and other reactions to construct drug core scaffolds |
| Materials | Structural modifier for liquid crystal monomers and OLED hole-transport materials | Converted to boronic ester derivatives for cross-coupling reactions, enabling synergistic modulation of molecular polarity and energy levels via methoxy–methyl–nitrile functionality |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical state, and presence of visible impurities under natural light or standard illumination. |
| Purity (Content) | High-Performance Liquid Chromatography (HPLC) | Utilize reversed-phase columns (e.g., C18) with UV detection (typically at 254 nm); quantify the main component by comparison with a reference standard. |
| Gas Chromatography (GC) | Applicable to samples with good volatility; use FID detector for quantitative analysis based on retention time and peak area. | |
| Structure Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Use ¹H-NMR and ¹³C-NMR to confirm compound structure by comparing characteristic peak chemical shifts with literature values. |
| Fourier Transform Infrared Spectroscopy (FT-IR) | Identify functional groups via characteristic absorption peaks (e.g., —CN triple bond stretching ~2200 cm⁻¹, Ar-OCH₃ ~1250 cm⁻¹, etc.). | |
| Mass Spectrometry (MS) | Determine molecular ion peak ([M]⁺ ≈ m/z 147) using EI-MS or ESI-MS to verify molecular weight and assist in structural elucidation. | |
| Water Content | Karl Fischer Titration | Quantify water content precisely through the reaction between iodine and sulfur dioxide in an anhydrous environment; suitable for trace moisture detection. |
| Residual Solvents | Gas Chromatography (GC) | Detect organic solvents potentially remaining from production processes (e.g., methanol, ethanol, acetone), following pharmacopoeial or regulatory guidelines (e.g., ICH Q3C). |
| Melting Point | Melting Point Instrument Method | Determine initial and final melting temperatures using automatic or capillary melting point apparatuses, used for identification and preliminary purity assessment. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) | After sample digestion, measure levels of heavy metals such as lead, cadmium, mercury, and arsenic to ensure compliance with pharmaceutical or industrial safety standards. |
| Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Enable higher sensitivity detection of trace metal impurities; suitable for high-purity product requirements. | |
| Chloride/Sulfate | Ion Chromatography (IC) or Turbidimetry | Determine inorganic anion impurity levels; commonly used for limit testing in active pharmaceutical ingredients. |
| Cyanide Residue | Spectrophotometry or Ion Chromatography | Detect residual free cyanide from synthesis processes to ensure toxic substances are controlled within safe limits. |
| Test Item | Specification |
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| Appearance | White crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 62–66°C |
| Identification (NMR) | Conforms to reference standard |
| Identification (IR) | Conforms to reference standard |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.