China Factory Direct
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| CAS number | 35621-01-3 |
| Product name | 4-Aminopiperidine dihydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Reagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a synthetic drug intermediate for antiviral, antitumor, and central nervous system agents | Produced via reaction of 4-aminopiperidine with hydrochloric acid to form the dihydrochloride salt; employed as a chiral building block in condensation, reduction, and alkylation steps |
| Chemical Synthesis | Used as a nitrogen-containing basic intermediate in organic synthesis | Acts as an amino donor in multistep syntheses, participating in Schiff base formation, amide coupling, or cyclization reactions |
| Research & Development | Applied in structural modification and active molecule construction during new drug discovery | Serves as a starting material for structural derivatization in high-throughput screening and structure–activity relationship (SAR) studies |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Acid-Base Titration | Quantifies active compound by titration with standardized NaOH solution using potentiometric or indicator endpoint detection. |
| Related Substances | HPLC-UV | Separates and quantifies impurities using reversed-phase HPLC with UV detection at 210–230 nm. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric reaction with iodine in pyridine-methanol solvent system. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing at 700–800 C. |
| Heavy Metals | ICP-OES | Quantifies Pb, Cd, Hg, As, and other metals by plasma excitation and elemental emission spectroscopy. |
| Chloride Content | Potentiometric Titration | Measures Cl- ions using silver nitrate titrant and silver-sulfide electrode detection. |
| pH of Aqueous Solution | pH Potentiometry | Determines acidity/basicity of a 1% w/v aqueous solution using calibrated pH electrode. |
| Specific Optical Rotation | Polarimetry | Measures chiral purity by detecting rotation of plane-polarized light at 589 nm. |
| Loss on Drying | Thermogravimetric Analysis | Determines volatile content by mass loss after drying at 105 C for 2 hours under vacuum or air. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry or wet dispersion particle size distribution based on light scattering patterns. |
| Microbial Limits | Membrane Filtration | Detects aerobic bacteria, yeasts, and molds using filtration, nutrient media incubation, and colony enumeration. |
| Residual Solvents | GC-FID | Identifies and quantifies residual solvents (e.g., methanol, acetone) by gas chromatography with flame ionization detection. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 215-220 °C (decomposes) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.2% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.