4-(4-BROMOPHENYL)BUTANOIC ACID Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 35656-89-4 |
| Product name | 4-(4-BROMOPHENYL)BUTANOIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-(4-BROMOPHENYL)BUTANOIC ACID
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-(4-BROMOPHENYL)BUTANOIC ACID Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-(4-BROMOPHENYL)BUTANOIC ACID
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of the anti-inflammatory drug ibuprofen | Used to prepare ibuprofen analogues via multi-step reactions including Knoevenagel condensation of bromoarenes with ethyl cyanoacetate, followed by hydrolysis and reduction; also employed in constructing COX-2 inhibitor lead compounds containing a bromophenylbutyric acid motif |
| Organic Synthesis | Key building block for bromoaryl fatty acids | Applied as a bifunctional reagent linking electrophilic aryl rings to aliphatic chains, participating in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to construct drug molecule or functional material scaffolds |
| Materials Science | Synthesis intermediate for liquid crystal monomers and organic semiconductor precursors | Processed via esterification, debromination, or further functional group transformations to incorporate liquid crystal core structures (e.g., biphenyl/terphenyl units) or serve as a π-conjugated side-chain modification unit in the synthesis of OLED hole-transport materials |
Manufacturing Quality Control of 4-(4-BROMOPHENYL)BUTANOIC ACID
| Test Item | Common Test Methods | Method Summary |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical state, and presence of foreign matter under natural or standard lighting; typically it should be white to off-white crystalline powder. |
| Identification | Infrared Spectroscopy (IR) High-Performance Liquid Chromatography (HPLC) Proton Nuclear Magnetic Resonance (¹H NMR) |
- IR: Record the infrared absorption spectrum and compare characteristic functional group peaks (e.g., carboxylic O-H, C=O, aromatic C=C) with reference spectra. - HPLC: Retention time matches that of the reference standard under specified chromatographic conditions. - ¹H NMR: Confirm molecular structural features through chemical shifts and integration ratios (e.g., aromatic protons, methylene chains, carboxylic acid protons). |
| Assay | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with methanol-water or acetonitrile-water as mobile phase, detect using a UV detector (typically at 220–254 nm), and calculate the main component content by external standard method; generally requires ≥98.0%. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Employ gradient elution to separate the main component from potential impurities (e.g., starting material 4-bromobenzene, intermediates, oxidation or decarboxylation by-products). Control individual and total impurity limits using area normalization or a correction factor-based main component self-dilution method. |
| Residual Solvents | Gas Chromatography (GC) | Headspace or direct injection with polar or non-polar capillary columns and FID detection to determine residual organic solvents from synthesis (e.g., toluene, ethanol, dichloromethane), complying with ICH Q3C limits. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Constant Temperature Atmospheric Drying | Dry the sample to constant weight at 105°C and measure percentage weight loss to assess moisture and volatile content; typically requires ≤0.5%. |
| Sulfated Ash / Residue on Ignition | High-Temperature Ashing Method | Char the sample and then ignite at 700–800°C to constant weight to determine inorganic residue; generally requires ≤0.1%. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Digest the sample and quantify heavy metal elements such as lead, cadmium, mercury, and arsenic; must comply with pharmacopoeial or ICH Q3D limits (typically total heavy metals ≤20 ppm). |
Technical Specifications of 4-(4-BROMOPHENYL)BUTANOIC ACID
| Test Item | Specification |
|---|---|
| Appearance | White to light yellow crystalline powder |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 124–128°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-(4-BROMOPHENYL)BUTANOIC ACID
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-(4-BROMOPHENYL)BUTANOIC ACID
Safety Information of 4-(4-BROMOPHENYL)BUTANOIC ACID
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4-(4-BROMOPHENYL)BUTANOIC ACID
Industrial 4-(4-BROMOPHENYL)BUTANOIC ACID Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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